SCHEMBL284865

SCHEMBL284865

NCCCCC(=O)CC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.64
CYP2D6 P10635 1/20 0.64
LMNA P02545 4/20 0.61
KMT2A Q03164 3/20 0.61
BLM P54132 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
THRB P10828 2/20 0.61
MEN1 O00255 1/20 0.61
ALDH1A1 P00352 1/20 0.61
PLG P00747 1/20 0.61
ALOX15 P16050 1/20 0.61
SLC6A2 P23975 1/20 0.61
RECQL P46063 1/20 0.61
SLC6A3 Q01959 1/20 0.61
TSHR P16473 2/20 0.52
GABRR1 P24046 2/20 0.52
GABRR3 A8MPY1 1/20 0.52
GABRP O00591 1/20 0.52
GABRD O14764 1/20 0.52
HDAC3 O15379 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18342688 0.98 LMNA (0.65) NFKB1CYP2D6LMNAKMT2ABLM
SCHEMBL284981 0.92 LMNA (0.62) NFKB1CYP2D6LMNAKMT2ABLM
Hydrochloric Acid SCHEMBL27636882 0.90 LMNA (0.59) NFKB1CYP2D6LMNAKMT2ABLM
SCHEMBL9185822 0.87 LMNA (0.53) NFKB1CYP2D6LMNAKMT2AALDH1A1
SCHEMBL11438692 0.84 TSHR (0.56) NFKB1LMNAKMT2ATHRBMEN1
SCHEMBL6265240 0.84 TSHR (0.56) NFKB1LMNAKMT2ATHRBMEN1
SCHEMBL8751902 0.84 TSHR (0.56) NFKB1LMNAKMT2ATHRBMEN1
SCHEMBL3122983 0.82 LMNA (0.43) NFKB1CYP2D6LMNAKMT2ABLM
SCHEMBL11276320 0.81
SCHEMBL503966 0.81 LMNA (0.65) NFKB1CYP2D6LMNAKMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230022727-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA INC (US) 2023-01-26 US claimed
EP-2995925-B1 COMPOSITION FOR HISTOCHEMICAL PROCESSING VENTANA MED SYST INC (US) 2021-12-15 EP claimed
US-20190330670-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2019-10-31 US claimed
EP-2995925-A1 COMPOSITION FOR HISTOCHEMICAL PROCESSING Ventana Medical Systems, Inc. (US) 2016-03-16 EP claimed
US-20140178929-A1 COMPOSITIONS COMPRISING NANOMATERIALS AND METHOD FOR USING SUCH COMPOSITIONS FOR HISTOCHEMICAL PROCESSES VENTANA MEDICAL SYSTEMS, INC. (US) 2014-06-26 US claimed
US-8703490-B2 Compositions comprising nanomaterials and method for using such compositions for histochemical processes VENTANA MEDICAL SYSTEMS, INC. (US) 2014-04-22 US claimed
US-20130303723-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2013-11-14 US claimed
WO-2012177721-A1 MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2012-12-27 WO claimed
EP-2427544-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID Genomatica, Inc. (US) 2012-03-14 EP claimed
US-20110091897-A1 COMPOSITIONS COMPRISING NANOMATERIALS AND METHOD FOR USING SUCH COMPOSITIONS FOR HISTOCHEMICAL PROCESSES VENTANA MEDICAL SYSTEMS, INC. 2011-04-21 US claimed
EP-2300799-A2 COMPOSITIONS COMPRISING NANOMATERIALS AND METHOD FOR USING SUCH COMPOSITIONS FOR HISTOCHEMICAL PROCESSES Ventana Medical Systems, Inc. (US) 2011-03-30 EP claimed
US-20100317069-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2010-12-16 US claimed
WO-2010129936-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID GENOMATICA, INC. (US) 2010-11-11 WO claimed
WO-2009149013-A2 COMPOSITIONS COMPRISING NANOMATERIALS AND METHOD FOR USING SUCH COMPOSITIONS FOR HISTOCHEMICAL PROCESSES VENTANA MEDICAL SYSTEMS, INC. (US) 2009-12-10 WO claimed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 US disclosed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 US disclosed
CN-114728871-B Microorganisms and methods for reducing byproducts 基因组股份公司 2024-12-27 CN disclosed
US-7713753-B2 Dual-level self-assembled patterning method and apparatus fabricated using the method SEAGATE TECHNOLOGY LLC (US) 2010-05-11 US disclosed
US-20100051904-A1 Dual-Level Self-Assembled Patterning Method and Apparatus Fabricated Using the Method SEAGATE TECHNOLOGY LLC (US) 2010-03-04 US disclosed
WO-2009149013-A2 COMPOSITIONS COMPRISING NANOMATERIALS AND METHOD FOR USING SUCH COMPOSITIONS FOR HISTOCHEMICAL PROCESSES VENTANA MEDICAL SYSTEMS, INC. (US) 2009-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 NFKB1 2164/4885CYP2D6 1829/4885LMNA 2536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.