Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 9/20 | 0.56 |
| ▸ | SCD | O00767 | 6/20 | 0.52 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851988 | 0.88 | KLKB1 (0.62) | KLKB1SCD5NPC1RAB9A | |
| SCHEMBL2857899 | 0.83 | KLKB1 (0.56) | KLKB1RAB9ALMNA | |
| SCHEMBL2863128 | 0.82 | TAAR1 (0.47) | SCDSCD5NPC1RAB9ALMNA | |
| SCHEMBL951879 | 0.80 | POLB (0.60) | KLKB1SCDSCD5TDP1POLB | |
| SCHEMBL2850615 | 0.79 | KLKB1 (0.73) | KLKB1 | |
| SCHEMBL2854366 | 0.78 | KLKB1 (0.80) | KLKB1 | |
| SCHEMBL2857801 | 0.76 | LMNA (0.67) | KLKB1LMNA | |
| SCHEMBL28614480 | 0.76 | HIF1A (0.79) | LMNAPOLBTHRB | |
| SCHEMBL1972631 | 0.75 | HDAC2 (0.71) | NPC1RAB9ALMNATP53GAA | |
| SCHEMBL16712957 | 0.73 | ROCK1 (0.63) | NAMPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |