Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | SCD | O00767 | 14/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852630 | 0.89 | TAAR1 (0.52) | TAAR1NPC1GAARAB9ALMNA | |
| SCHEMBL2852519 | 0.89 | TAAR1 (0.59) | TAAR1NPC1GAARAB9A | |
| SCHEMBL2854712 | 0.88 | TAAR1 (0.54) | TAAR1NPC1GAARAB9ACNR1 | |
| SCHEMBL2848658 | 0.87 | LMNA (0.46) | TAAR1SCD5NPC1GAARAB9A | |
| SCHEMBL2857813 | 0.87 | TAAR1 (0.55) | TAAR1NPC1GAARAB9ACNR1 | |
| SCHEMBL2848393 | 0.84 | TAAR1 (0.48) | TAAR1SCDSCD5NPC1GAA | |
| SCHEMBL2859353 | 0.84 | TAAR1 (0.66) | TAAR1NPC1GAARAB9ACNR1 | |
| SCHEMBL2852329 | 0.83 | TAAR1 (0.49) | TAAR1NPC1GAARAB9APOLB | |
| SCHEMBL2848652 | 0.82 | KLKB1 (0.56) | SCDSCD5NPC1GAARAB9A | |
| SCHEMBL2325744 | 0.81 | SCD (0.50) | SCDSCD5POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |