Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8865234 | 0.80 | ALDH1A1 (0.33) | CDK2CCNA2CCNA1ALDH1A1CYP2C19 | |
| SCHEMBL28483907 | 0.75 | — | — | |
| SCHEMBL8724985 | 0.74 | ALDH1A1 (0.33) | ALDH1A1CYP2C19 | |
| SCHEMBL6316984 | 0.71 | CHUK (0.32) | ALDH1A1CYP2C19 | |
| SCHEMBL29903490 | 0.69 | POLB (0.31) | ALDH1A1CYP2C19 | |
| SCHEMBL887977 | 0.69 | POLB (0.31) | ALDH1A1CYP2C19 | |
| SCHEMBL11238497 | 0.69 | CDK2 (0.35) | CDK2CCNA2CCNA1CDK1CDK4 | |
| SCHEMBL435598 | 0.67 | LIMK1 (0.37) | ALDH1A1CYP2C19 | |
| Formic Acid SCHEMBL28960072 | 0.67 | — | — | |
| SCHEMBL28387294 | 0.66 | CCNA2 (0.36) | CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112062726-B | Preparation method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 苏州开元民生科技股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-112062726-A | Preparation method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 苏州开元民生科技股份有限公司 | 2020-12-11 | — | — | CN | claimed |
| CN-112062726-B | Preparation method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 苏州开元民生科技股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112062726-A | Preparation method of 2-amino-4, 6-dichloro-5-formamido pyrimidine | 苏州开元民生科技股份有限公司 | 2020-12-11 | — | — | CN | disclosed |