Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | ARAF | P10398 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317905 | 1.00 | TDP1 (0.60) | TDP1SIRT6MAPTALDH1A1LMNA | |
| SCHEMBL1031276 | 0.87 | TDP1 (0.61) | TDP1SIRT6MAPTALDH1A1LMNA | |
| SCHEMBL10784720 | 0.87 | TDP1 (0.70) | TDP1SIRT6MAPTALDH1A1MEN1 | |
| SCHEMBL1027039 | 0.85 | TDP1 (0.61) | TDP1SIRT6MAPTALDH1A1LMNA | |
| SCHEMBL2424186 | 0.85 | TDP1 (0.61) | TDP1SIRT6MAPTALDH1A1LMNA | |
| SCHEMBL23111304 | 0.83 | TDP1 (0.67) | TDP1SIRT6MAPTALDH1A1BRAF | |
| SCHEMBL1027323 | 0.83 | TDP1 (0.57) | TDP1SIRT6MAPTALDH1A1MEN1 | |
| SCHEMBL17530357 | 0.82 | TDP1 (0.76) | TDP1SIRT6MAPTALDH1A1BRAF | |
| SCHEMBL1027047 | 0.81 | TDP1 (0.58) | TDP1SIRT6MAPTALDH1A1LMNA | |
| SCHEMBL1026867 | 0.81 | TDP1 (0.55) | TDP1SIRT6MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094248-B | Substituted benzothiazole compound and application thereof | 中国人民解放军海军军医大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-112094248-A | Substituted benzothiazole compound and application thereof | 中国人民解放军海军军医大学 | 2020-12-18 | — | — | CN | disclosed |