SCHEMBL28487541

SCHEMBL28487541

NC1(NCc2ccco2)N=CN=C2N=CN=C21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.34
GAA P10253 1/20 0.34
EPHX2 P34913 3/20 0.33
CHRM2 P08172 1/20 0.33
MEN1 O00255 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
MAPK1 P28482 2/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SHMT2 P34897 1/20 0.32
KCNH3 Q9ULD8 1/20 0.32
ALDH1A1 P00352 2/20 0.32
DNMT1 P26358 1/20 0.32
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
ADRA2A P08913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL752582 0.80
SCHEMBL29827740 0.78 EPHX2 (0.39) KMT2AEPHX2MEN1TDP1KDM4E
SCHEMBL28195211 0.70
SCHEMBL28492418 0.64
SCHEMBL94056 0.62 MAOA (0.37)
SCHEMBL17744967 0.62
SCHEMBL6897683 0.61
SCHEMBL8429764 0.60
SCHEMBL11132899 0.60 ADRA2A (0.41) KMT2AGAAMEN1KDM4ELMNA
SCHEMBL6381754 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112058244-A Preparation method and application of 6-benzylaminopurine magnetic molecularly imprinted nanoparticles 湖南农业大学 2020-12-11 CN disclosed