Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28494383 | 0.87 | ALDH1A1 (0.43) | ALDH1A1PDE4BKMT2AL3MBTL1MEN1 | |
| SCHEMBL28485211 | 0.84 | ALDH1A1 (0.42) | ALDH1A1PDE4BKMT2AL3MBTL1MEN1 | |
| SCHEMBL28481675 | 0.83 | PDE4B (0.55) | ALDH1A1PDE4BKMT2AL3MBTL1MEN1 | |
| SCHEMBL13612528 | 0.82 | ALDH1A1 (0.48) | ALDH1A1PDE4BKMT2AL3MBTL1MEN1 | |
| SCHEMBL29910774 | 0.81 | LMNA (0.51) | L3MBTL1LMNA | |
| SCHEMBL19919421 | 0.81 | LMNA (0.51) | L3MBTL1LMNA | |
| SCHEMBL28618122 | 0.80 | KMT2A (0.45) | ALDH1A1KMT2AL3MBTL1MEN1RAB9A | |
| SCHEMBL12370829 | 0.80 | HSP90AA1 (0.47) | ALDH1A1PDE4BKMT2AL3MBTL1MEN1 | |
| SCHEMBL28487000 | 0.79 | HPGD (0.50) | ALDH1A1PDE4BKMT2AL3MBTL1MEN1 | |
| SCHEMBL28608292 | 0.78 | POLB (0.46) | ALDH1A1PDE4BKMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |