Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1757449 | 0.82 | HRH4 (0.41) | KDM4EGAAHTTSMN1; SMN2TDP1 | |
| SCHEMBL24629725 | 0.79 | KMT2A (0.52) | KDM4EGAAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL7006443 | 0.78 | XDH (0.37) | KMT2APOLBRXFP1MEN1NPC1 | |
| SCHEMBL1757881 | 0.78 | HRH4 (0.32) | ARKEAP1NFE2L2CYP2A6 | |
| SCHEMBL12970315 | 0.77 | GRIN2D (0.47) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14115020 | 0.76 | HRH4 (0.45) | KDM4EGAAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL23685896 | 0.75 | EIF4A3 (0.34) | — | |
| SCHEMBL1757914 | 0.72 | MAPK1 (0.37) | KDM4EGAAKMT2AL3MBTL1KEAP1 | |
| SCHEMBL3361286 | 0.72 | DAO (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14115029 | 0.72 | AXL (0.52) | HTTALDH1A1PTGS1PTGS2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047870-B | Preparation method of 7-alkyl indole derivative | 浙江工业大学 | 2021-10-12 | — | — | CN | disclosed |
| CN-112047870-A | Preparation method of 7-alkyl indole derivative | 浙江工业大学 | 2020-12-08 | — | — | CN | disclosed |