Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 15/20 | 0.60 |
| ▸ | DDO | Q99489 | 6/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12970315 | 0.83 | GRIN2D (0.47) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3420670 | 0.81 | DAO (0.64) | DAODDO | |
| SCHEMBL3421507 | 0.81 | DAO (0.58) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3422795 | 0.79 | DAO (0.62) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL16767856 | 0.75 | DAO (1.00) | DAODDOHSD17B10 | |
| SCHEMBL5973354 | 0.75 | GRIN1 (0.67) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28487705 | 0.72 | KDM4E (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3363037 | 0.72 | DAO (0.61) | DAODDO | |
| SCHEMBL12970080 | 0.70 | BRD4 (0.43) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3361624 | 0.70 | DAO (0.58) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |