SCHEMBL4372862

SCHEMBL4372862

CC(C)(C)OC(=O)C1(C)CCNCC1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.34
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33
OPRM1 P35372 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23211002 0.98 FFAR3 (0.33) FFAR3KDM4EKMT2AOPRM1CYP4F2
SCHEMBL17040615 0.89
SCHEMBL15055670 0.83 KDM4E (0.35) KDM4EKMT2AOPRM1CYP4F2CYP4A11
SCHEMBL4189013 0.82 KDM4E (0.32) KDM4EKMT2A
SCHEMBL5722406 0.81 FFAR3 (0.39) FFAR3CYP4F2CYP4A11
SCHEMBL28487708 0.80 KDM4E (0.33) KDM4EKMT2AOPRM1CYP4F2CYP4A11
SCHEMBL21564990 0.79 FFAR3 (0.37) FFAR3KMT2ACYP4F2CYP4A11
SCHEMBL28675361 0.79 DGAT1 (0.31) KMT2A
SCHEMBL2146137 0.78 OPRM1 (0.34) KDM4EKMT2AOPRM1CYP4F2CYP4A11
SCHEMBL4372857 0.78 KDM4E (0.32) KDM4EKMT2AOPRM1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4566675-A2 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS Incyte Corporation (US) 2025-06-11 EP disclosed
US-20250171443-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2025-05-29 US disclosed
CN-119613400-A Heterocyclic compounds as immunomodulators 因赛特公司 2025-03-14 CN disclosed
US-12247026-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2025-03-11 US disclosed
EP-4212529-B1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORP (US) 2025-01-29 EP disclosed
US-20240400587-A1 BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF NURIX THERAPEUTICS INC (US) 2024-12-05 US disclosed
CN-112135824-B Heterocyclic compounds as immunomodulators 因赛特公司 2024-11-05 CN disclosed
WO-2024227104-A1 BIFUNCTIONAL COMPOUNDS FOR DEGRADING BRAF VIA UBIQUITIN PROTEOSOME PATHWAY NURIX THERAPEUTICS, INC. (US) 2024-10-31 WO disclosed
EP-4430052-A1 BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF Nurix Therapeutics, Inc. (US) 2024-09-18 EP disclosed
US-12091426-B2 Bifunctional degraders of hematopoietic progenitor kinase and therapeutic uses thereof NURIX THERAPEUTICS, INC. (US) 2024-09-17 US disclosed
US-11124511-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2021-09-21 US disclosed
EP-3774791-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS Incyte Corporation (US) 2021-02-17 EP disclosed
CN-112135824-A Heterocyclic compounds as immunomodulators 因赛特公司 2020-12-25 CN disclosed
US-20200255424-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2020-08-13 US disclosed
US-10669271-B2 Heterocyclic compounds as immunomodulators INCYTE CORPORATION (US) 2020-06-02 US disclosed
US-20190300524-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION 2019-10-03 US disclosed
WO-2019191707-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS INCYTE CORPORATION (US) 2019-10-03 WO disclosed
US-20120135975-A1 Substituted Esters as Cannabinoid-1 Receptor Modulators MERCK & CO., INC. (US) 2012-05-31 US disclosed
EP-2024334-A2 SUBSTITUTED ESTERS AS CANNABINOID-1 RECEPTOR MODULATORS Merck & Co., Inc. (US) 2009-02-18 EP disclosed
WO-2007136607-A2 SUBSTITUTED ESTERS AS CANNABINOID-1 RECEPTOR MODULATORS MERCK & CO., INC. (US) 2007-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190300524-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS CD74, IL2, ICOS FFAR3 3744/4885KDM4E 3674/4885KMT2A 4005/4885
US-10669271-B2 Heterocyclic compounds as immunomodulators CD74, IL2, ICOS FFAR3 3744/4885KDM4E 3674/4885KMT2A 4005/4885
US-20200255424-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS CD74, IL2, ICOS FFAR3 3744/4885KDM4E 3674/4885KMT2A 4005/4885
US-11124511-B2 Heterocyclic compounds as immunomodulators CD74, IL2, ICOS FFAR3 3744/4885KDM4E 3674/4885KMT2A 4005/4885
US-12247026-B2 Heterocyclic compounds as immunomodulators CD74, IL2, ICOS FFAR3 3744/4885KDM4E 3674/4885KMT2A 4005/4885
US-20120135975-A1 Substituted Esters as Cannabinoid-1 Receptor Modulators CNR1, CNR2, FAAH FFAR3 59/4885KDM4E 2066/4885KMT2A 2455/4885
US-12091426-B2 Bifunctional degraders of hematopoietic progenitor kinase and therapeutic uses thereof TTK, HIPK1, CLK1 FFAR3 4544/4885KDM4E 1185/4885KMT2A 733/4885
US-20240400587-A1 BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF TTK, HIPK1, CLK1 FFAR3 4544/4885KDM4E 1185/4885KMT2A 733/4885
US-20250171443-A1 HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS CD74, IL2, ICOS FFAR3 3744/4885KDM4E 3674/4885KMT2A 4005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.