Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28489104 | 0.98 | LMNA (0.42) | LMNAALOX5L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL1286910 | 0.84 | ESR1 (0.46) | LMNAALDH1A1TRPV1TDP1 | |
| SCHEMBL23116504 | 0.84 | MASP2 (0.40) | ALOX5ALDH1A1 | |
| SCHEMBL29074393 | 0.82 | HTT (0.51) | LMNAALDH1A1 | |
| SCHEMBL7020082 | 0.82 | HDAC3 (0.53) | LMNAALDH1A1TDP1HPGD | |
| SCHEMBL837643 | 0.82 | HDAC3 (0.53) | LMNAALDH1A1TDP1HPGD | |
| SCHEMBL29261487 | 0.80 | LMNA (0.61) | LMNAALOX5L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL29074405 | 0.79 | PRCP (0.50) | ALDH1A1HPGD | |
| SCHEMBL4996799 | 0.77 | LMNA (0.49) | LMNAALOX5L3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL29074380 | 0.75 | MAPK1 (0.48) | LMNAALDH1A1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848494-B | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-111848494-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2020-10-30 | — | — | CN | disclosed |