Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | GFER | P55789 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | GAA | P10253 | 6/20 | 0.70 |
| ▸ | POLB | P06746 | 4/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767339 | 0.88 | MEN1 (0.90) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL29377327 | 0.88 | MEN1 (0.90) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL28548462 | 0.84 | MEN1 (0.82) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL12172367 | 0.84 | NPC1 (0.72) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL6322764 | 0.83 | ALDH1A1 (0.76) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL12351220 | 0.83 | MEN1 (1.00) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL276208 | 0.83 | NPC1 (0.73) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL29899998 | 0.83 | NPC1 (0.73) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL15443912 | 0.83 | PRMT1 (0.82) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL17513608 | 0.82 | MEN1 (0.70) | NPC1RAB9AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875545-A | Directional synthesis method and application of 6-substituted benzimidazole derivative | 安阳师范学院 | 2020-11-03 | — | — | CN | disclosed |