Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.73 |
| ▸ | RAB9A | P51151 | 8/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.70 |
| ▸ | GFER | P55789 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29899998 | 1.00 | NPC1 (0.73) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL13599850 | 0.91 | NPC1 (0.81) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL13183701 | 0.89 | NPC1 (0.78) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL20677813 | 0.87 | NPC1 (0.75) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL3336231 | 0.86 | NPC1 (0.62) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL21976473 | 0.85 | METAP2 (0.59) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL9909430 | 0.85 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL6124301 | 0.85 | NPC1 (0.71) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL12172367 | 0.84 | NPC1 (0.72) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL13299660 | 0.84 | NPC1 (0.72) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251760-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 1994-01-26 | — | — | EP | claimed |
| US-5140055-A | Improved high speed grip performance | BRIDGESTONE CORPORATION (JP) | 1992-08-18 | — | — | US | claimed |
| CN-116810216-A | Water-soluble pre-flux and surface treatment method | 株式会社田村制作所 | 2023-09-29 | — | — | CN | disclosed |
| US-20220047554-A1 | COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS | UNIVERSITY OF VIRGINIA | 2022-02-17 | — | — | US | disclosed |
| CN-113620886-A | Preparation method of 2-substituted benzimidazole derivative | 北京成宇化工有限公司 | 2021-11-09 | — | — | CN | disclosed |
| US-11090289-B2 | Compositions and methods for blocking sodium channels | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-08-17 | — | — | US | disclosed |
| US-11090289-B2 | Compositions and methods for blocking sodium channels | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-08-17 | — | — | US | disclosed |
| CN-108165260-B | Organic electroluminescent material and preparation method and application thereof | 北京燕化集联光电技术有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-108191766-B | Benzimidazole organic electroluminescent material and preparation method and application thereof | 北京燕化集联光电技术有限公司 | 2020-09-15 | — | — | CN | disclosed |
| US-10434041-B2 | Water-in-oil emulsion cosmetic composition | SHISEIDO COMPANY, LTD. (JP) | 2019-10-08 | — | — | US | disclosed |
| WO-2018140504-A1 | COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS | PATEL MANOJ K (US) | 2018-08-02 | — | — | WO | disclosed |
| US-5476947-A | Excellent rust preventing effect, useful as corrosion resistance protective coating in printed wiring boards | MEC CO., LTD. (JP) | 1995-12-19 | — | — | US | disclosed |
| US-5435860-A | Corrosion resistance for printed circuits | MEC CO., LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0251760-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 1994-01-26 | — | — | EP | disclosed |
| EP-0551112-A1 | Benzimidazole derivative and composition for treating copper and copper alloy surfaces comprising the same | MEC CO., Ltd. (JP) | 1993-07-14 | — | — | EP | disclosed |
| US-5169912-A | Hydrolyzable oxygen bonding with epoxide; silica, titania; high performance coatings, adhesives | KEEHAN DONALD J (US) | 1992-12-08 | — | — | US | disclosed |
| US-5140055-A | Improved high speed grip performance | BRIDGESTONE CORPORATION (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5026816-A | Reaction product of diglycidyl ether of (bisphenol a or resorcinol) with metallic oxide in presence of imidazole catalyst | KEEHAN DONALD J (US) | 1991-06-25 | — | — | US | disclosed |
| US-4880892-A | PHOSPHONIUM OR PHOSPHORANE CATALYST, PROTECTIVE COATINGS | CIBA-GEIGY CORPORATION (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0251760-A2 | Rubber composition | Bridgestone Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10434041-B2 | Water-in-oil emulsion cosmetic composition | H1-0, H1-2, LBR | NPC1 1444/4885RAB9A 3699/4885KDM4E 3462/4885 |
| US-11090289-B2 | Compositions and methods for blocking sodium channels | SCN3A, SCN1B, SCN2B | NPC1 483/4885RAB9A 2068/4885KDM4E 4354/4885 |
| US-20220047554-A1 | COMPOSITIONS AND METHODS FOR BLOCKING SODIUM CHANNELS | SCN3A, SCN1B, SCN2B | NPC1 483/4885RAB9A 2068/4885KDM4E 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.