Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.70 |
| ▸ | RELA | Q04206 | 5/20 | 0.70 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | HIF1AN | Q9NWT6 | 5/20 | 0.56 |
| ▸ | ODC1 | P11926 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29271160 | 0.94 | NFKB1 (0.70) | NFKB1NFKB2RELAACHEHIF1AN | |
| SCHEMBL29271161 | 0.94 | NFKB1 (0.70) | NFKB1NFKB2RELAACHEHIF1AN | |
| SCHEMBL28489290 | 0.93 | NFKB1 (0.71) | NFKB1NFKB2RELAACHEHIF1AN | |
| SCHEMBL14296455 | 0.92 | ACHE (0.70) | NFKB1NFKB2RELAACHEHIF1AN | |
| SCHEMBL31376266 | 0.92 | ACHE (0.70) | NFKB1NFKB2RELAACHEHIF1AN | |
| SCHEMBL29271171 | 0.91 | NFKB1 (0.85) | NFKB1NFKB2RELAACHEHIF1AN | |
| SCHEMBL29271170 | 0.91 | NFKB1 (0.85) | NFKB1NFKB2RELAACHEHIF1AN | |
| Xanthohumol C SCHEMBL14249680 | 0.89 | NFKB1 (0.65) | NFKB1NFKB2RELAACHEHIF1AN | |
| SCHEMBL31376253 | 0.89 | NFKB1 (0.62) | NFKB1NFKB2RELAACHEHIF1AN | |
| Xanthohumol C SCHEMBL30066955 | 0.89 | NFKB1 (0.65) | NFKB1NFKB2RELAACHEHIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047917-A | Xanthohumol derivative and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2020-12-08 | — | — | CN | claimed |
| CN-112047917-B | Xanthohumol derivative and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2023-10-31 | — | — | CN | disclosed |
| CN-112047917-A | Xanthohumol derivative and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2020-12-08 | — | — | CN | disclosed |