SCHEMBL2848935

SCHEMBL2848935

CCCC1C(=O)NC(=O)N(C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4A O75164 1/20 0.34
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
ALOX15 P16050 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
ATM Q13315 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9007459 0.89 ALDH1A1 (0.55) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL2851785 0.83 ALDH1A1 (0.41) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL9334296 0.81 ALDH1A1 (0.38) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL9363498 0.81 ALDH1A1 (0.38) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL2672871 0.74 PDE5A (0.45) MEN1KMT2ALMNATSHRGAA
SCHEMBL1426706 0.72 ALDH1A1 (0.52) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL14345693 0.71 MEN1 (0.34) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL12408237 0.71 NPSR1 (0.43) ALDH1A1HPGDKDM4EMEN1MAPT
SCHEMBL17472455 0.71 ALDH1A1 (0.49) ALDH1A1KMT2APOLBLMNATSHR
SCHEMBL17294157 0.70 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746489-A1 PHOTOLABILE BARBITURATE COMPOUNDS 3M Innovative Properties Company (US) 2020-12-09 EP claimed
CN-111630072-A Photolabile barbiturate compound 3M创新有限公司 2020-09-04 CN claimed
WO-2019152187-A1 PHOTOLABILE BARBITURATE COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-08-08 WO claimed
US-8853297-B2 Method and means for infiltrating enamel lesions CHARITE UNIVERSITATSMEDIZIN BERLIN (DE) 2014-10-07 US claimed
US-20090304622-A1 METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS CHARITE-UNIVERSITATSMEDIZIN BERLIN (DE) 2009-12-10 US claimed
EP-2023884-A1 METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS Ernst Mühlbauer GmbH & Co.KG (DE) 2009-02-18 EP claimed
WO-2007131725-A1 METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS CHARITE-UNIVERSITÄTSMEDIZIN BERLIN (DE) 2007-11-22 WO claimed
CN-116635452-B Free radically polymerizable crosslinking agent, curable composition, and adhesive therefrom 3M INNOVATIVE PROPERTIES CO. (US) 2026-05-26 CN disclosed
US-12600885-B2 Composition including monomer with a carboxylic acid group, monomer with a hydroxyl group, an alkyl monomer, and crosslinker and related article and method 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-14 US disclosed
US-12398301-B2 Adhesives comprising cyclic imide addition-fragmentation and adhesion agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-08-26 US disclosed
US-12378340-B2 Crosslinkers and curable compositions including the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-08-05 US disclosed
EP-4448672-B1 CURABLE PRECURSOR OF AN ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-05-28 EP disclosed
US-20250101278-A1 CURABLE PRECURSOR OF AN ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2025-03-27 US disclosed
US-7132462-B2 Two-component dental materials having a low setting temperature 3M ESPE AG (DE) 2006-11-07 US disclosed
EP-0923924-B1 Dental adhesive kit SUN MEDICAL CO LTD (JP) 2005-03-09 EP disclosed
US-6852775-B1 Polymerizable dental compositions 3M ESPE AG (DE) 2005-02-08 US disclosed
US-20040254261-A1 Dental composition GC CORPORATION (JP) 2004-12-16 US disclosed
US-20030158288-A1 Two-component dental materials having a low setting temperature 3M DEUTSCHLAND GMBH (DE) 2003-08-21 US disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed
EP-0923924-A2 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 1999-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600885-B2 Composition including monomer with a carboxylic acid group, monomer with a hydroxyl group, an alkyl monomer, and crosslinker and related article and method RAD51, HACL2, COL2A1 ALDH1A1 577/4885HPGD 1508/4885KDM4E 3173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.