Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BRD1 | O95696 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28903712 | 0.87 | MAPT (0.42) | MAPTTSHRALDH1A1USP2HSP90AA1 | |
| SCHEMBL28903732 | 0.85 | MAPT (0.41) | MAPTTSHRCYP19A1ALDH1A1USP2 | |
| SCHEMBL28509158 | 0.85 | CA1 (0.45) | MAPTTSHRCYP19A1ALDH1A1USP2 | |
| SCHEMBL28498697 | 0.82 | KMT2A (0.44) | CYP19A1ALDH1A1MEN1KMT2APKM | |
| SCHEMBL28497453 | 0.81 | CYP3A4 (0.43) | MAPTALDH1A1USP2MEN1KMT2A | |
| SCHEMBL28498349 | 0.80 | ALDH1A1 (0.50) | MAPTTSHRALDH1A1 | |
| SCHEMBL28489446 | 0.72 | LSS (0.41) | CYP19A1ALDH1A1KMT2A | |
| SCHEMBL28498477 | 0.72 | CYP3A4 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5882252 | 0.71 | MEN1 (0.39) | MAPTTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28493442 | 0.70 | KMT2A (0.49) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110932-B | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112110932-A | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |