Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28489905 | 0.88 | PKM (0.49) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL28498697 | 0.85 | KMT2A (0.44) | KMT2AMEN1GAAHPGDALDH1A1 | |
| SCHEMBL28497517 | 0.85 | MAPT (0.49) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL28487989 | 0.85 | MAPT (0.54) | KMT2AMEN1SMN1; SMN2GAAHPGD | |
| SCHEMBL29095265 | 0.84 | HPGD (0.49) | KMT2AMEN1SMN1; SMN2LMNAGAA | |
| SCHEMBL28498454 | 0.82 | MAPT (0.43) | KMT2AMEN1GAAHPGDMAPT | |
| SCHEMBL19392334 | 0.76 | KMT2A (0.75) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28498338 | 0.74 | ALDH1A1 (0.65) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9968019 | 0.74 | LMNA (0.84) | KMT2AMEN1SMN1; SMN2LMNAHPGD | |
| SCHEMBL28493441 | 0.71 | ALDH1A1 (0.52) | KMT2AMEN1SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110932-B | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112110932-A | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |