Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22227672 | 0.84 | ROCK2 (0.61) | ROCK2 | |
| SCHEMBL22227678 | 0.83 | ROCK2 (0.65) | ROCK2 | |
| SCHEMBL22227674 | 0.83 | ROCK2 (0.58) | ROCK2 | |
| SCHEMBL28489708 | 0.82 | ROCK2 (0.63) | ROCK2 | |
| SCHEMBL22227679 | 0.79 | ROCK2 (0.60) | ROCK2 | |
| SCHEMBL28902528 | 0.78 | ROCK2 (0.64) | ROCK2 | |
| SCHEMBL22227654 | 0.77 | ROCK2 (0.64) | ROCK2 | |
| SCHEMBL22227686 | 0.76 | ROCK2 (0.55) | ROCK2 | |
| SCHEMBL21406840 | 0.75 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL18048662 | 0.75 | ROCK2 (1.00) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406426-B | Cyclic ureas as ROCK inhibitors | 百时美施贵宝公司 | 2020-11-20 | — | — | CN | claimed |