Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696971 | 1.00 | ALDH1A1 (0.49) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1437767 | 0.95 | ALDH1A1 (0.50) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1696964 | 0.93 | ALDH1A1 (0.46) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL195776 | 0.93 | ALDH1A1 (0.43) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL6794551 | 0.92 | ALDH1A1 (0.42) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1696991 | 0.90 | ALDH1A1 (0.41) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1696968 | 0.90 | GSR (0.44) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1696978 | 0.89 | ALDH1A1 (0.40) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL30773222 | 0.83 | ALDH1A1 (0.49) | ALDH1A1PKMFOLH1CYP1A2CYP2C19 | |
| SCHEMBL8530125 | 0.82 | ALDH1A1 (0.51) | ALDH1A1PKMFOLH1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112055749-A | Use of FUBP1 inhibitors for the treatment of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2020-12-08 | — | — | CN | disclosed |