Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490356 | 1.00 | ALDH1A1 (0.49) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1437767 | 0.95 | ALDH1A1 (0.50) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1696964 | 0.93 | ALDH1A1 (0.46) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL195776 | 0.93 | ALDH1A1 (0.43) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL6794551 | 0.92 | ALDH1A1 (0.42) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1696991 | 0.90 | ALDH1A1 (0.41) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1696968 | 0.90 | GSR (0.44) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL1696978 | 0.89 | ALDH1A1 (0.40) | ALDH1A1PKMGSRRNPEPCPB2 | |
| SCHEMBL30773222 | 0.83 | ALDH1A1 (0.49) | ALDH1A1PKMFOLH1CYP1A2CYP2C19 | |
| SCHEMBL8530125 | 0.82 | ALDH1A1 (0.51) | ALDH1A1PKMFOLH1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119479794-A | Method for identifying multiple lysine modification sites based on EPDCC technology | 江南大学 | 2025-02-18 | — | — | CN | claimed |
| CN-118692563-A | Method for predicting multiple lysine modification sites based on ClusterCentroids undersampling technology | 江南大学 | 2024-09-24 | — | — | CN | claimed |
| EP-2596122-B1 | MODULATORS FOR SIRT5 AND ASSAYS FOR SCREENING SAME | UNIV CORNELL (US) | 2018-09-05 | — | — | EP | claimed |
| US-9932621-B2 | Modulators for Sirt5 and assays for screening same | CORNELL UNIVERSITY (US) | 2018-04-03 | — | — | US | claimed |
| US-20150057236-A1 | MODULATORS FOR SIRT5 AND ASSAYS FOR SCREENING SAME | CORNELL UNIVERSITY (US) | 2015-02-26 | — | — | US | claimed |
| US-8658394-B2 | Methods, cells and systems for incorporating non-canonical amino acids into proteins | WATERSTONE PHARMACEUTICALS (CN) | 2014-02-25 | — | — | US | claimed |
| EP-2596122-A2 | MODULATORS FOR SIRT5 AND ASSAYS FOR SCREENING SAME | Cornell University (US) | 2013-05-29 | — | — | EP | claimed |
| US-20120237971-A1 | METHODS, CELLS AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS | WATERSTONE PHARMACEUTICALS (CN) | 2012-09-20 | — | — | US | claimed |
| WO-2012092629-A2 | METHODS, CELLS, AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS | WATERSTONE PHARMACEUTICALS (CN) | 2012-07-05 | — | — | WO | claimed |
| WO-2012006391-A2 | MODULATORS FOR SIRT5 AND ASSAYS FOR SCREENING SAME | CORNELL UNIVERSITY (US) | 2012-01-12 | — | — | WO | claimed |
| US-20260021186-A1 | Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2026-01-22 | — | — | US | disclosed |
| EP-4565325-A2 | FATTY ACID-D-AMINO ACID PEPTIDES CONJUGATES AS ANAPLEROTIC COMPOUNDS FOR USE IN TREATING PROPIONIC ACIDEMIA, METHYLMALONIC ACIDURIAS, AND ENERGY METABOLIC DISORDERS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-06-11 | — | — | EP | disclosed |
| CN-119855613-A | Fatty acid-D-amino acid peptide conjugates as anaplerotic compounds for the treatment of hyperuricemia, methylmalonic urine disorder and energy metabolism disorders | 匹兹堡大学高等教育联邦体系 | 2025-04-18 | — | — | CN | disclosed |
| CN-119479794-A | Method for identifying multiple lysine modification sites based on EPDCC technology | 江南大学 | 2025-02-18 | — | — | CN | disclosed |
| US-20250019540-A1 | PROTEIN POLYURETHANE ALLOYS COMPRISING A SUCCINYLATED PROTEIN AND METHODS OF MAKING THE SAME | MODERN MEADOW INC (US) | 2025-01-16 | — | — | US | disclosed |
| US-20120183948-A1 | Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from epsilon-amino lysine moieties | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| WO-2012092629-A2 | METHODS, CELLS, AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS | WATERSTONE PHARMACEUTICALS (CN) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012006391-A2 | MODULATORS FOR SIRT5 AND ASSAYS FOR SCREENING SAME | CORNELL UNIVERSITY (US) | 2012-01-12 | — | — | WO | disclosed |
| JP-2003159055-A | MONOCLONAL ANTIBODY, HYBRID CELL AND METHOD FOR PRODUCING THE SAME | NOF CORP | 2003-06-03 | — | — | JP | disclosed |
| WO-1993018759-A1 | A DNA TRANSPORTER SYSTEM AND METHOD OF USE | BAYLOR COLLEGE OF MEDICINE (US) | 1993-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120183948-A1 | Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from epsilon-amino lysine moieties | EMG1, SPR, SHMT1 | ALDH1A1 3027/4885PKM 979/4885GSR 2458/4885 |
| US-20260021186-A1 | Fatty Acid-D-Amino Acid Peptides Conjugates as Anaplerotic Compounds for Use in Treating Propionic Acidemia, Methylmalonic Acidurias, and Energy Metabolic Disorders | HADHB, HADHA, HADH | ALDH1A1 623/4885PKM 1274/4885GSR 1750/4885 |
| US-20150057236-A1 | MODULATORS FOR SIRT5 AND ASSAYS FOR SCREENING SAME | SIRT5, SIRT6, SIRT1 | ALDH1A1 2504/4885PKM 1524/4885GSR 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.