Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16969523 | 0.83 | TDP1 (0.47) | PLK1PLK3TDP1TSHRSMN1; SMN2 | |
| SCHEMBL28666950 | 0.81 | TDP1 (0.46) | PLK1PLK3TDP1TSHRSMN1; SMN2 | |
| SCHEMBL4938054 | 0.81 | TDP1 (0.46) | PLK1PLK3TDP1TSHRSMN1; SMN2 | |
| SCHEMBL887829 | 0.80 | GPR35 (0.47) | PLK1PLK3TDP1ALDH1A1MAPT | |
| SCHEMBL28899633 | 0.80 | GPR35 (0.47) | PLK1PLK3TDP1ALDH1A1MAPT | |
| SCHEMBL27321459 | 0.79 | TSHR (0.55) | TDP1TSHRSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL18666841 | 0.78 | TSHR (0.48) | PLK1PLK3TDP1TSHRSMN1; SMN2 | |
| SCHEMBL10777337 | 0.78 | TDP1 (0.48) | TDP1TSHRSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL4048581 | 0.76 | TDP1 (0.47) | TDP1TSHRSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL27884727 | 0.76 | GPR35 (0.50) | TDP1TSHRSMN1; SMN2HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088151-A | Process for producing fluoromethyl derivative | 大金工业株式会社 | 2020-12-15 | — | — | CN | disclosed |