Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 7/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289006 | 1.00 | ENPEP (0.52) | ENPEPALOX15BLMPMP22KMT2A | |
| SCHEMBL285212 | 0.88 | ENPEP (0.65) | ENPEPBLMPMP22KMT2AALDH1A1 | |
| SCHEMBL289092 | 0.88 | ENPEP (0.65) | ENPEPBLMPMP22KMT2AALDH1A1 | |
| SCHEMBL4283479 | 0.88 | ALOX15 (0.54) | ENPEPALOX15BLMPMP22KMT2A | |
| SCHEMBL288131 | 0.88 | ALOX15 (0.54) | ENPEPALOX15BLMPMP22KMT2A | |
| SCHEMBL27999571 | 0.88 | ALOX15 (0.54) | ENPEPALOX15BLMPMP22KMT2A | |
| Hydrochloric Acid SCHEMBL17287148 | 0.86 | ENPEP (0.63) | ENPEPBLMPMP22KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5108419 | 0.84 | ENPEP (0.43) | ENPEPALOX15BLMPMP22KMT2A | |
| SCHEMBL288933 | 0.82 | ENPEP (0.59) | ENPEPALOX15BLMPMP22KMT2A | |
| SCHEMBL6678989 | 0.82 | ENPEP (0.67) | ENPEPALOX15BLMPMP22KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012177721-A1 | MICROORGANISMS FOR PRODUCING 6-AMINOCAPROIC ACID | GENOMATICA, INC. (US) | 2012-12-27 | — | — | WO | claimed |
| EP-2427544-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | Genomatica, Inc. (US) | 2012-03-14 | — | — | EP | claimed |
| WO-2010129936-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID | GENOMATICA, INC. (US) | 2010-11-11 | — | — | WO | claimed |
| CN-104284891-B | Conformationally constrained, fully synthetic macrocyclic compounds | 波利弗尔股份公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104284891-A | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG | 2015-01-14 | — | — | CN | disclosed |