Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28497701 | 0.86 | PTGS2 (0.46) | KMT2ABCHEALDH1A1HPGDPOLB | |
| SCHEMBL28498848 | 0.86 | KMT2A (0.48) | KMT2AACHEMGAMF12AMY1A | |
| SCHEMBL28505828 | 0.86 | KMT2A (0.48) | KMT2AACHEMGAMF12AMY1A | |
| SCHEMBL28495147 | 0.85 | PTGS2 (0.43) | KMT2AACHEALDH1A1POLBL3MBTL1 | |
| SCHEMBL28495086 | 0.84 | PTGS2 (0.46) | KMT2AACHEF12POLBAKR1C3 | |
| SCHEMBL28496079 | 0.84 | PTGS2 (0.46) | KMT2AACHEMGAMAMY1AGAA | |
| SCHEMBL28495418 | 0.83 | PLAU (0.39) | KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL28490523 | 0.83 | HPGD (0.38) | KMT2AALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL28490532 | 0.81 | PTGS2 (0.48) | KMT2AF12GAAALDH1A1HPGD | |
| SCHEMBL28486883 | 0.80 | KMT2A (0.69) | KMT2AACHEALDH1A1BLMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028811-A | 4-iodo-indole compound and preparation method thereof | 平顶山学院 | 2020-12-04 | — | — | CN | claimed |
| CN-112028811-B | 4-iodo-indole compound and preparation method thereof | 平顶山学院 | 2022-03-22 | — | — | CN | disclosed |
| CN-112028811-A | 4-iodo-indole compound and preparation method thereof | 平顶山学院 | 2020-12-04 | — | — | CN | disclosed |