Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490523 | 0.92 | HPGD (0.38) | PTGS2L3MBTL1TSHRRAB9AKMT2A | |
| SCHEMBL28495086 | 0.88 | PTGS2 (0.46) | PTGS2KMT2AACHEPOLB | |
| SCHEMBL28496079 | 0.88 | PTGS2 (0.46) | PTGS2RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL28497701 | 0.88 | PTGS2 (0.46) | PTGS2L3MBTL1RAB9AKMT2AKDM4E | |
| SCHEMBL28488401 | 0.86 | ELANE (0.47) | PTGS2L3MBTL1KMT2A | |
| SCHEMBL28487030 | 0.86 | PARP1 (0.40) | PTGS2L3MBTL1ALDH1A1 | |
| SCHEMBL249819 | 0.85 | ALDH1A1 (0.33) | L3MBTL1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL28495797 | 0.85 | AKR1C1 (0.42) | TSHRRAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL28492579 | 0.85 | KMT2A (0.48) | L3MBTL1KMT2AALDH1A1ACHEPOLB | |
| SCHEMBL28500871 | 0.83 | PTGS2 (0.43) | PTGS2L3MBTL1TSHRRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112028811-A | 4-iodo-indole compound and preparation method thereof | 平顶山学院 | 2020-12-04 | — | — | CN | claimed |
| CN-112028811-B | 4-iodo-indole compound and preparation method thereof | 平顶山学院 | 2022-03-22 | — | — | CN | disclosed |
| CN-112028811-A | 4-iodo-indole compound and preparation method thereof | 平顶山学院 | 2020-12-04 | — | — | CN | disclosed |