⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476385 | 0.93 | HSD17B10 (0.56) | — | |
| SCHEMBL29263924 | 0.85 | HSD17B10 (0.67) | — | |
| SCHEMBL13784211 | 0.77 | — | — | |
| SCHEMBL17299382 | 0.77 | — | — | |
| SCHEMBL25623600 | 0.76 | HSD17B10 (0.56) | — | |
| SCHEMBL13931708 | 0.76 | HSD17B10 (0.56) | — | |
| SCHEMBL21076254 | 0.76 | HSD17B10 (0.56) | — | |
| SCHEMBL26728614 | 0.76 | HSD17B10 (0.61) | — | |
| SCHEMBL8183345 | 0.75 | — | — | |
| SCHEMBL20773628 | 0.75 | ACHE (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384776-A | A kind of 5-fluor-uracil derivative and its preparation method and application | 南京友怡医药科技有限公司 | 2019-02-26 | — | — | CN | claimed |
| US-20110129430-A1 | HYDROXYBENZYL OR HYDROXYPYRANONEMETHYL ESTERS AS TYROSINASE INHIBITORS | EASTMAN CHEMICAL COMPANY (US) | 2011-06-02 | — | — | US | claimed |
| CN-101680008-A | Hydroxyphenylmethyl or hydroxypyrone methyl esters as tyrosinase inhibitors | EASTMAN CHEM CO | 2010-03-24 | — | — | CN | claimed |
| US-20080306144-A1 | Hydroxybenzyl or hydroxypyranonemethyl esters as tyrosinase inhibitors | EASTMAN CHEMICAL COMPANY | 2008-12-11 | — | — | US | claimed |
| EP-0847999-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-21 | — | — | EP | claimed |
| US-5849745-A | N-benzylpiperazine compounds | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | claimed |
| EP-0847999-A1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-06-17 | — | — | EP | claimed |
| CN-110220961-A | A kind of L-arginine detection method and sensor based on the complex film modified electrode of polypeptide | 长沙理工大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-109384776-A | A kind of 5-fluor-uracil derivative and its preparation method and application | 南京友怡医药科技有限公司 | 2019-02-26 | — | — | CN | disclosed |
| EP-2428577-B1 | Preparation of tyrosinase-inhibiting hydroxybenzyl and hydroxypyranonemethyl esters | EASTMAN CHEM CO (US) | 2014-01-22 | — | — | EP | disclosed |
| CN-101680008-B | Hydroxyphenylmethyl or hydroxypyrone methyl esters as tyrosinase inhibitors | EASTMAN CHEM CO | 2013-06-26 | — | — | CN | disclosed |
| EP-2428577-A1 | Preparation of tyrosinase-inhibiting hydroxybenzyl and hydroxypyranonemethyl esters | EASTMAN CHEMICAL COMPANY (US) | 2012-03-14 | — | — | EP | disclosed |
| US-20110129430-A1 | HYDROXYBENZYL OR HYDROXYPYRANONEMETHYL ESTERS AS TYROSINASE INHIBITORS | EASTMAN CHEMICAL COMPANY (US) | 2011-06-02 | — | — | US | disclosed |
| US-20080306144-A1 | Hydroxybenzyl or hydroxypyranonemethyl esters as tyrosinase inhibitors | EASTMAN CHEMICAL COMPANY | 2008-12-11 | — | — | US | disclosed |
| EP-0847999-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-21 | — | — | EP | disclosed |
| US-5849745-A | N-benzylpiperazine compounds | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5849745-A | N-benzylpiperazine compounds | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| CN-1192436-A | New-benzylpiperazine compounds, process for their prepn. and pharmaceutical compositions which contain them | ADIR (FR) | 1998-09-09 | — | — | CN | disclosed |
| EP-0847999-A1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-06-17 | — | — | EP | disclosed |
| EP-0847999-A1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-06-17 | — | — | EP | disclosed |