SCHEMBL1476385

SCHEMBL1476385

[CH2]CCCCC1CCSS1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.56
KMT2A Q03164 2/20 0.56
TARDBP Q13148 2/20 0.56
CYP2C9 P11712 1/20 0.56
MEN1 O00255 1/20 0.56
NR1I2 O75469 1/20 0.56
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
POLB P06746 1/20 0.56
THRB P10828 1/20 0.56
TSHR P16473 1/20 0.56
ACHE P22303 1/20 0.56
APEX1 P27695 1/20 0.56
RECQL P46063 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
SAE1 Q9UBE0 1/20 0.56
UBA2 Q9UBT2 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284930 0.93
SCHEMBL29263924 0.89 HSD17B10 (0.67) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL19160682 0.79 HSD17B10 (0.53) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL26728614 0.78 HSD17B10 (0.61) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL16312506 0.78 HSD17B10 (0.61) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL7841853 0.78 KMT2A (0.61) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL25623600 0.78 HSD17B10 (0.56) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL13931708 0.78 HSD17B10 (0.56) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL21076254 0.78 HSD17B10 (0.56) HSD17B10KMT2ATARDBPCYP2C9MEN1
SCHEMBL20773628 0.77 ACHE (0.47) HSD17B10KMT2ATARDBPCYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828283-B1 PEPTIDE WITH GOLD BINDING AND EGFR RECEPTOR AFFINITY AND SAME ATTACHED TO GOLD NANOSTRUCTURE UNIV MISSOURI (US) 2018-04-18 EP claimed
US-9766252-B2 Peptide with gold binding and EGFR receptor affinity and same attached to gold nanostructure THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2017-09-19 US claimed
US-20160041188-A1 PEPTIDE WITH GOLD BINDING AND EGFR RECEPTOR AFFINITY AND SAME ATTACHED TO GOLD NANOSTRUCTURE THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2016-02-11 US claimed
EP-2828283-A1 PEPTIDE WITH GOLD BINDING AND EGFR RECEPTOR AFFINITY AND SAME ATTACHED TO GOLD NANOSTRUCTURE The Curators Of The University Of Missouri (US) 2015-01-28 EP claimed
WO-2013142200-A1 PEPTIDE WITH GOLD BINDING AND EGFR RECEPTOR AFFINITY AND SAME ATTACHED TO GOLD NANOSTRUCTURE THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2013-09-26 WO claimed
EP-1390378-B1 PHARMACEUTICALLY ACTIVE URIDINE ESTERS TROMMSDORFF ARZNEIMITTEL (DE) 2009-06-17 EP claimed
US-7396826-B2 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2008-07-08 US claimed
US-20040121979-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2004-06-24 US claimed
US-5830994-A TETRAPEPTIDE; AMTIINFLAMMATORY AGENT, ANTIALLERGENS, COSMETICS; MELANOCTE STIMULATING HORMONE INSTITUT EUROPEEN DE BIOLOGIE CELLULAIRE (FR) 1998-11-03 US claimed
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-03-17 US disclosed
CN-107875401-B Photo-crosslinking antibacterial nano-particles and preparation method and application thereof 东南大学 2020-02-18 CN disclosed
WO-2020007234-A1 ALKYNYL(HETERO)AROMATIC COMPOUND FOR INHIBITING PROTEIN KINASE ACTIVITY 深圳市塔吉瑞生物医药有限公司 2020-01-09 WO disclosed
EP-1996734-B1 METHOD AND APPARATUS FOR TARGET DETECTION USING ELECTRODE-BOUND VIRUSES UNIV CALIFORNIA (US) 2018-08-01 EP disclosed
EP-2828283-B1 PEPTIDE WITH GOLD BINDING AND EGFR RECEPTOR AFFINITY AND SAME ATTACHED TO GOLD NANOSTRUCTURE UNIV MISSOURI (US) 2018-04-18 EP disclosed
US-20050043269-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL 2005-02-24 US disclosed
US-20040121979-A1 Pharmaceutically active uridine esters TROMMSDORFF GMBH & CO. KG ARZNEIMITTEL (DE) 2004-06-24 US disclosed
US-6369098-B1 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-.GAMMA. (PPAR.GAMMA.) AND/OR PPAR.ALPHA TREATMENT OF ENDOCRINE, SKIN, CARDIOVASCULAR, IMMUNOLOGICAL, NEUROLOGICAL, NEUROPSYCHIATRIC, NEOPLASTIC AND CHRONIC VIRAL DISEASES OF VARIOUS ORGANS BETHESDA PHARMACEUTICALS, INC. 2002-04-09 US disclosed
WO-2002013812-A1 METHODS FOR TREATING INFLAMMATORY DISEASES PERSHADSINGH HARRIHAR A (US) 2002-02-21 WO disclosed
WO-2001025226-A1 DITHIOLANE DERIVATIVES BETHESDA PHARMACEUTICALS, INC. (US) 2001-04-12 WO disclosed
US-5552085-A CONTROLLING CORROSION ON THE METALLIC SURFACES OF DISTILLATION COLUMNS NALCO CHEMICAL COMPANY (US) 1996-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040121979-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR1 HSD17B10 141/4885KMT2A 3902/4885TARDBP 3224/4885
US-20050043269-A1 Pharmaceutically active uridine esters UMPS, UGDH, FFAR3 HSD17B10 169/4885KMT2A 3774/4885TARDBP 2874/4885
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines STT3B, STT3A, DDOST HSD17B10 441/4885KMT2A 2780/4885TARDBP 4640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.