Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | PDE8A | O60658 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887930 | 0.91 | PPARG (0.54) | PPARGAGTR1AGTR2 | |
| SCHEMBL12357098 | 0.82 | PPARG (0.53) | PPARGAGTR1AGTR2 | |
| SCHEMBL4012974 | 0.81 | PPARG (0.48) | PPARGCYP19A1AGTR1AGTR2 | |
| SCHEMBL1892312 | 0.81 | PPARG (0.58) | PPARGAGTR1 | |
| SCHEMBL1890655 | 0.79 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL1891285 | 0.79 | PPARG (0.54) | PPARGAGTR1 | |
| SCHEMBL4164574 | 0.79 | PPARG (0.60) | PPARGAGTR1AGTR2 | |
| SCHEMBL4010303 | 0.79 | PPARG (0.55) | PPARGAGTR1AGTR2 | |
| SCHEMBL1889130 | 0.78 | PPARG (0.49) | PPARGAGTR1 | |
| SCHEMBL12349090 | 0.77 | AGTR1 (0.46) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256115-A1 | Heteromonocyclic compound and use thereof | Takeda Pharmaceutical Company Limited (JP) | 2010-12-01 | — | — | EP | disclosed |