Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892480 | 0.89 | PPARG (0.63) | PPARGAGTR1AGTR2 | |
| SCHEMBL4309681 | 0.85 | PPARG (0.48) | PPARGCYP19A1AGTR1CNR1EDNRA | |
| SCHEMBL1891211 | 0.83 | PPARG (0.56) | PPARGAGTR1AGTR2 | |
| SCHEMBL2849368 | 0.81 | PPARG (0.44) | PPARGCYP19A1AGTR1AGTR2 | |
| SCHEMBL5061753 | 0.80 | AGTR1 (0.47) | PPARGAGTR1EDNRAKDM4EL3MBTL1 | |
| SCHEMBL1892564 | 0.80 | PPARG (0.59) | PPARGAGTR1AGTR2 | |
| SCHEMBL1892153 | 0.78 | PPARG (0.46) | PPARGAGTR1AGTR2 | |
| SCHEMBL1886369 | 0.78 | PPARG (0.64) | PPARGAGTR1AGTR2 | |
| SCHEMBL9843787 | 0.77 | PDE4A (0.44) | PPARGCYP19A1AGTR1AGTR2 | |
| SCHEMBL12349095 | 0.77 | PPARG (0.60) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |