Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623804 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C9CYP2C19KDM4E | |
| SCHEMBL1554320 | 0.86 | KDM4E (0.53) | KDM4ECFDTSHRCYP4F2CYP4A11 | |
| SCHEMBL3501336 | 0.84 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C9CYP2C19MAPK8 | |
| SCHEMBL13751481 | 0.84 | KDM4E (0.43) | CYP1A2CYP2D6CYP2C9CYP2C19KDM4E | |
| SCHEMBL24803694 | 0.84 | KDM4E (0.43) | CYP1A2CYP2D6CYP2C9CYP2C19KDM4E | |
| SCHEMBL4413571 | 0.81 | TSHR (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19KDM4E | |
| SCHEMBL5132516 | 0.81 | PKM (0.56) | CYP1A2CYP2D6CYP2C9CYP2C19TSHR | |
| SCHEMBL7639873 | 0.81 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C9CYP2C19TSHR | |
| SCHEMBL7929984 | 0.81 | KDM4E (0.47) | KDM4ETSHRCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL3927306 | 0.81 | KDM4E (0.47) | KDM4ECFDTSHRCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878533-A | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-112805001-B | Inhibition of αvβ6 integrin | 莫菲克医疗股份有限公司 | 2024-07-23 | — | — | CN | disclosed |
| US-11905240-B2 | Cyclopropyl ethylene compound and arthropod pest control composition containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11905240-B2 | Cyclopropyl ethylene compound and arthropod pest control composition containing same | CYC1, EEF1A1, RPS4X | CYP1A2 108/4885CYP2D6 1237/4885CYP2C9 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.