SCHEMBL284946

SCHEMBL284946

ClC(Cl)(Cl)c1cc[c]cc1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534268 0.84 TSHR (0.42) TSHR
SCHEMBL8558513 0.79
SCHEMBL7370103 0.77
SCHEMBL20486967 0.77
SCHEMBL5402636 0.77
SCHEMBL9529779 0.77
SCHEMBL28383052 0.77
SCHEMBL20486905 0.77 TSHR (0.33) TSHR
SCHEMBL9201518 0.77
SCHEMBL9816151 0.75 TSHR (0.67) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1686 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854683-A Coumarin thiazole derivative and preparation method and application thereof 中北大学 2023-10-10 CN claimed
CN-114105993-B Synthesis method of chiral pyrroloimidazole compound 大连理工大学 2023-03-10 CN claimed
CN-114105993-A Synthesis method of chiral pyrroloimidazole compound 大连理工大学 2022-03-01 CN claimed
CN-109942553-B Synthesis and conversion method of chiral 3,4, 6-trisubstituted tetrahydro 2H-pyran-2-one compound 大连理工大学 2020-09-29 CN claimed
CN-109942553-A A kind of synthesis of tri- substituted-tetrahydro 2H- pyran-2-one compound of chirality 3,4,6- and its method for transformation 大连理工大学 2019-06-28 CN claimed
EP-3197507-A1 MALODOR REDUCTION COMPOSITIONS The Procter and Gamble Company (US) 2017-08-02 EP claimed
WO-2016049389-A1 MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
EP-2415763-B1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA UBE INDUSTRIES (JP) 2016-01-27 EP claimed
US-20140113907-A1 PYRIDYLAMINOACETIC ACID COMPOUND UBE INDUSTRIES, LTD. (JP) 2014-04-24 US claimed
EP-2520570-A1 AMINOPYRIDINE COMPOUND Ube Industries, Ltd. (JP) 2012-11-07 EP claimed
EP-0641786-B1 Process for producing optically active alcohol SUMITOMO CHEMICAL CO (JP) 1997-08-20 EP claimed
EP-0639556-B1 Process for the preparation of trifluoromethylanilines HOECHST AG (DE) 1997-03-05 EP claimed
EP-0641786-A1 Process for producing optically active alcohol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-08 EP claimed
US-5144039-A Reducing prochiral ketone with metal borohydride modified with optically active amino alcohol in presence of ether or sulfide SUMITOMO ELECTRIC COMPANY, LIMITED (JP) 1992-09-01 US claimed
EP-0381434-A1 Process for producing optically active alcohol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-08-08 EP claimed
EP-0161480-B1 N-IODINE PROPARGYL-CHLOROMETHANESULFONAMIDE BAYER AG (DE) 1987-06-03 EP claimed
EP-0161480-A1 N-iodine propargyl-chloromethanesulfonamide BAYER AG (DE) 1985-11-21 EP claimed
EP-0062773-B1 4-Phenyl-1,2,3-thiadiazoles as herbicide extenders STAUFFER CHEMICAL COMPANY (US) 1984-12-05 EP claimed
EP-0062773-A1 4-Phenyl-1,2,3-thiadiazoles as herbicide extenders STAUFFER CHEMICAL COMPANY (US) 1982-10-20 EP claimed
US-4215129-A 2-(2,4-DICHLOROPHENYL)-5-ARYL-1,3,4-OXADIAZOLE THE DOW CHEMICAL COMPANY (US) 1980-07-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140113907-A1 PYRIDYLAMINOACETIC ACID COMPOUND PTGER2, PTGER1, PTGDR2 TSHR 987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.