Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545084 | 1.00 | TSHR (0.67) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL1538637 | 0.89 | TSHR (0.56) | TSHRMAPK1HIF1ACYP3A4TDP1 | |
| SCHEMBL7949296 | 0.89 | TSHR (0.56) | TSHRMAPK1HIF1A | |
| SCHEMBL196830 | 0.86 | TSHR (0.57) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL11231213 | 0.86 | TSHR (0.53) | TSHRMAPK1HIF1A | |
| SCHEMBL526434 | 0.83 | ESR1 (0.52) | TSHRHIF1AMEN1KMT2ALMNA | |
| SCHEMBL1538589 | 0.83 | TSHR (0.55) | TSHRLMNACYP19A1TDP1 | |
| SCHEMBL3869048 | 0.83 | TSHR (0.50) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL11209484 | 0.83 | TSHR (0.55) | TSHRMAPK1LMNATDP1 | |
| SCHEMBL11254085 | 0.83 | TSHR (0.50) | TSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449811-A1 | IMPROVED PROCESS FOR SYNTHESIS OF HETEROCYCLIC POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1991-10-09 | — | — | EP | disclosed |