Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495234 | 0.90 | HDAC1 (0.65) | HDAC1HDAC6KDM4EL3MBTL1POLB | |
| SCHEMBL28509075 | 0.75 | HDAC6 (1.00) | HDAC1HDAC6KDM4EL3MBTL1POLB | |
| SCHEMBL28504884 | 0.75 | HDAC6 (0.75) | HDAC1HDAC6L3MBTL1POLB | |
| SCHEMBL29558498 | 0.71 | HDAC6 (0.71) | HDAC1HDAC6KDM4EL3MBTL1POLB | |
| SCHEMBL26830394 | 0.70 | HDAC1 (0.71) | HDAC1 | |
| SCHEMBL12223773 | 0.70 | HTR2A (0.51) | KDM4ECHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29558554 | 0.70 | HDAC6 (0.66) | HDAC1HDAC6L3MBTL1POLB | |
| SCHEMBL18355624 | 0.67 | HTR2A (0.48) | CHRM4CHRM5CHRM1CHRM3OPRM1 | |
| SCHEMBL29558905 | 0.66 | HDAC1 (0.72) | HDAC1HDAC6L3MBTL1POLB | |
| SCHEMBL29558833 | 0.65 | HDAC1 (0.60) | HDAC1HDAC6L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943892-B | Histone deacetylase subtype inhibitor thioacetylarylamine compound and application thereof | 上海中泽医药科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-111943892-B | Histone deacetylase subtype inhibitor thioacetylarylamine compound and application thereof | 上海中泽医药科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-111943892-A | Histone deacetylase subtype inhibitor thioacetylarylamine compound and application thereof | 上海中泽医药科技有限公司 | 2020-11-17 | — | — | CN | disclosed |