Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 19/20 | 0.69 |
| ▸ | THRA | P10827 | 17/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660307 | 0.88 | THRB (0.81) | THRBTHRA | |
| SCHEMBL22668177 | 0.87 | THRB (0.73) | THRBTHRA | |
| SCHEMBL22668198 | 0.84 | THRB (0.78) | THRBTHRA | |
| SCHEMBL22660315 | 0.83 | THRB (0.76) | THRBTHRA | |
| SCHEMBL22660316 | 0.83 | THRA (0.46) | THRBTHRA | |
| SCHEMBL2927022 | 0.82 | THRB (1.00) | THRBTHRA | |
| SCHEMBL22668186 | 0.80 | THRB (0.68) | THRBTHRA | |
| SCHEMBL22660372 | 0.80 | THRB (0.42) | THRBTHRA | |
| SCHEMBL22660373 | 0.79 | THRB (0.44) | THRBTHRA | |
| SCHEMBL22668197 | 0.79 | THRB (0.72) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909137-B | Pyridazinone derivative and application thereof | 深圳微芯生物科技股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-111909137-A | Pyridazinone derivative and application thereof | 深圳微芯生物科技股份有限公司 | 2020-11-10 | — | — | CN | disclosed |