SCHEMBL2849549

SCHEMBL2849549

CCO[Si](OCC)(OCC)C(CC)NCCO

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
CNR1 P21554 1/20 0.31
ADRA1A P35348 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ABCC3 O15438 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10891054 0.87 LMNA (0.31) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL342542 0.83
SCHEMBL343092 0.80 ALDH1A1 (0.31)
SCHEMBL199875 0.80
SCHEMBL1136095 0.79
SCHEMBL6660616 0.78 ALDH1A1 (0.34)
SCHEMBL4272106 0.77 EPHX1 (0.35) KDM4E
SCHEMBL11741158 0.77
SCHEMBL29249230 0.77 EPHX1 (0.35) KDM4E
Ammonia Solution, Strong SCHEMBL3679851 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5770722-A Surface-bound, unimolecular, double-stranded DNA AFFYMETRIX, INC. (US) 1998-06-23 US claimed
US-8236493-B2 Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA AFFYMETRIX, INC. (US) 2012-08-07 US disclosed
US-20120164693-A1 METHODS OF ENZYMATIC DISCRIMINATION ENHANCEMENT AND SURFACE-BOUND DOUBLE-STRANDED DNA AFFYMETRIX, INC. (US) 2012-06-28 US disclosed
US-20120122104-A1 Triple-Stranded Nucleobase Structures and Uses Thereof APPLERA CORPORATION (US) 2012-05-17 US disclosed
WO-2010144348-A2 REDUCTION OF ANTIBIOTIC ACTIVITY OR CONCENTRATION IN BIOLOGICAL SAMPLES USING MOLECULARLY IMPRINTED POLYMERS BECTON, DICKINSON AND COMPANY (US) 2010-12-16 WO disclosed
US-20100216656-A1 METHODS OF ENZYMATIC DISCRIMINATION ENHANCEMENT AND SURFACE-BOUND DOUBLE-STRANDED DNA AFFYMETRIX, INC. (US) 2010-08-26 US disclosed
US-7718362-B2 DNA chip based genetic typing CAPITALBIO CORPORATION (CN) 2010-05-18 US disclosed
EP-1370696-A4 EXPRESSION PROFILES AND METHODS OF USE ORTHO CLINICAL DIAGNOSTICS INC (US) 2009-04-22 EP disclosed
WO-2009035554-A2 SUPERIOR STRUCTURE STABILITY AND SELECTIVITY OF HAIRPIN NUCLEIC ACID PROBES WITH AN L-DNA STEM UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2009-03-19 WO disclosed
US-20080220979-A1 Rapid Method To Detect Nucleic Acid Molecules CAPITALBIO CORPORATION (CN) 2008-09-11 US disclosed
EP-1021558-A1 SURFACE-BOUND, DOUBLE-STRANDED DNA PROTEIN ARRAYS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-07-26 EP disclosed
EP-1003912-A1 SURFACE-BOUND, BIMOLECULAR, DOUBLE-STRANDED DNA ARRAYS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-05-31 EP disclosed
WO-1999007888-A9 SURFACE-BOUND, BIMOLECULAR, DOUBLE-STRANDED DNA ARRAYS HARVARD COLLEGE (US) 1999-04-29 WO disclosed
WO-1999019510-A1 SURFACE-BOUND, DOUBLE-STRANDED DNA PROTEIN ARRAYS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1999-04-22 WO disclosed
WO-1999007888-A1 SURFACE-BOUND, BIMOLECULAR, DOUBLE-STRANDED DNA ARRAYS PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) 1999-02-18 WO disclosed
US-5770722-A Surface-bound, unimolecular, double-stranded DNA AFFYMETRIX, INC. (US) 1998-06-23 US disclosed
US-5679773-A SOLID PHASE SYNTHESIS AFFYMAX TECHNOLOGIES N.V (GB) 1997-10-21 US disclosed
WO-1996029088-A1 NOVEL PIPERAZINE DERIVATIVES AS TYPE IL-1 RECEPTOR ANTAGONISTS AFFYMAX TECHNOLOGIES N.V. (AN) 1996-09-26 WO disclosed
US-5556752-A Surface-bound, unimolecular, double-stranded DNA AFFYMETRIX, INC. (US) 1996-09-17 US disclosed
EP-0721016-A2 Nucleic acid library arrays, methods for synthesizing them and methods for sequencing and sample screening using them AFFYMAX TECHNOLOGIES N.V. (AN) 1996-07-10 EP disclosed