Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495663 | 0.87 | ELANE (0.49) | ELANETSHRSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL7778743 | 0.85 | ELANE (0.45) | ELANETSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7729786 | 0.85 | ELANE (0.47) | ELANETSHRALDH1A1MEN1KMT2A | |
| SCHEMBL1134975 | 0.84 | ELANE (0.46) | ELANETSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5887434 | 0.84 | ELANE (0.46) | ELANETSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5964086 | 0.84 | ELANE (0.49) | ELANETSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5887440 | 0.84 | ELANE (0.46) | ELANETSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7732985 | 0.84 | ELANE (0.46) | ELANETSHRSMN1; SMN2NPSR1MEN1 | |
| SCHEMBL5964258 | 0.83 | ELANE (0.43) | ELANEALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7977154 | 0.82 | ELANE (0.40) | ELANEALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809627-B1 | NOVEL BORNEOL DERIVATIVES, METHODS OF MANUFACTURING THEM, AND THEIR PHARMACEUTICAL USE | SCHERING AG (DE) | 2001-09-12 | — | — | EP | disclosed |
| US-6025507-A | Borneol derivatives, methods of manufacturing them, and their pharmaceutical use | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |
| EP-0809627-A1 | NOVEL BORNEOL DERIVATIVES, METHODS OF MANUFACTURING THEM, AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025392-A1 | NOVEL BORNEOL DERIVATIVES, METHODS OF MANUFACTURING THEM, AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |