Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.58 |
| ▸ | CES2 | O00748 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL27941168 | 0.98 | CES1 (0.56) | CES1CES2LMNATDP1L3MBTL1 | |
| SCHEMBL2238176 | 0.82 | TDP1 (0.56) | CES1CES2LMNATDP1L3MBTL1 | |
| SCHEMBL24188 | 0.82 | TDP1 (0.56) | CES1CES2LMNATDP1L3MBTL1 | |
| SCHEMBL2358014 | 0.82 | ATM (0.64) | CES1CES2LMNATDP1L3MBTL1 | |
| SCHEMBL11287856 | 0.80 | TDP1 (0.54) | CES1CES2LMNATDP1L3MBTL1 | |
| Water SCHEMBL27597000 | 0.80 | TDP1 (0.54) | CES1CES2LMNATDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27977560 | 0.80 | TDP1 (0.54) | CES1CES2LMNATDP1L3MBTL1 | |
| SCHEMBL7384862 | 0.80 | TDP1 (0.54) | CES1CES2LMNATDP1L3MBTL1 | |
| SCHEMBL157066 | 0.79 | CES1 (0.62) | CES1CES2LMNATDP1L3MBTL1 | |
| SCHEMBL1549080 | 0.79 | CES1 (0.62) | CES1CES2LMNATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482649-B | Stereospecific carbonyl reductases | UNIV RUTGERS | 2014-09-03 | — | — | CN | claimed |
| CN-101857887-B | Method for preparing optically pure aryl alcohol with cell-free extracts of recombinant strains by catalytic asymmetric conversion | UNIV JIANGNAN | 2012-11-14 | — | — | CN | claimed |
| CN-102482649-A | Stereospecific carbonyl reductases | UNIV RUTGERS | 2012-05-30 | — | — | CN | claimed |
| CN-101857887-A | Method for preparing optically pure aryl alcohol with cell-free extracts of recombinant strains by catalytic asymmetric conversion | UNIV JIANGNAN | 2010-10-13 | — | — | CN | claimed |
| CN-109195599-A | antifungal composition | 株式会社种探索研究所 | 2019-01-11 | — | — | CN | disclosed |
| CN-108373444-A | Fluorescence viologen derivative and its application and preparation method | 上海大学 | 2018-08-07 | — | — | CN | disclosed |
| CN-105431427-B | Novel PDE 4 inhibitor | 明治制果药业株式会社 | 2017-12-08 | — | — | CN | disclosed |
| CN-105431427-A | Novel PDE4 inhibitor | MEIJI SEIKA PHARMA CO LTD | 2016-03-23 | — | — | CN | disclosed |
| CN-105121395-A | Method to improve 1,1,3-trichloropropene and/or 3,3,3-trichloropropene selectivity during the dehydrochlorination of 1,1,1,3-tetrachloropropane | HONEYWELL INT INC | 2015-12-02 | — | — | CN | disclosed |
| CN-101857887-B | Method for preparing optically pure aryl alcohol with cell-free extracts of recombinant strains by catalytic asymmetric conversion | UNIV JIANGNAN | 2012-11-14 | — | — | CN | disclosed |
| CN-1688532-B | Compositions based on substituted 1, 3-diphenylprop-2-en-1-one derivatives, preparation and use thereof | GENFIT | 2012-07-11 | — | — | CN | disclosed |
| CN-102482649-A | Stereospecific carbonyl reductases | UNIV RUTGERS | 2012-05-30 | — | — | CN | disclosed |
| CN-1013443-B | PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 1991-08-07 | — | — | CN | disclosed |
| EP-0409164-A2 | Phenacylpyridiniothiocephalosporins | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4980496-A | Method for producing C1 to C5 alkyl nitrides | HOECHST CELANESE CORPORATION, A CORP. OF DE | 1990-12-25 | — | — | US | disclosed |
| EP-0383539-A1 | Production of alpha-chloro-alpha-oximino-4-hydroxy-acetophenone | HOECHST CELANESE CORPORATION (US) | 1990-08-22 | — | — | EP | disclosed |
| US-4910338-A | Production of α-chloro-α-oximino-4-hydroxyacetophenone | HOECHST CELANESE CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |
| CN-87100191-A | The hydroxy acid derivative of treatment diabetic complication | — | 1987-09-09 | — | — | CN | disclosed |
| CN-85104009-A | The method for preparing imdazole derivatives | — | 1986-11-19 | — | — | CN | disclosed |
| EP-0066378-A1 | Pharmaceutical spiro-hydantoin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-08 | — | — | EP | disclosed |