SCHEMBL2849600

SCHEMBL2849600

CCP(CC)c1ccccc1C(C)(N)c1ccccc1P(CC)CC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2856673 0.77 ALDH1A1 (0.33) SLC6A2TAAR1ALDH1A1TSHRTDP1
SCHEMBL2852140 0.75 ALDH1A1 (0.37) SLC6A2TAAR1ALDH1A1TSHRTDP1
SCHEMBL2912079 0.75 TP53 (0.36) ALDH1A1TSHR
SCHEMBL30616094 0.75 TP53 (0.36) ALDH1A1TSHR
SCHEMBL2850053 0.72 TDP1 (0.42) SLC6A2TAAR1ALDH1A1TSHRTDP1
SCHEMBL2854576 0.72 SLC6A2 (0.33) SLC6A2TAAR1ALDH1A1TSHRTDP1
SCHEMBL4438970 0.70 CYP3A4 (0.41) ALDH1A1TSHRTDP1
SCHEMBL4449690 0.69 TP53 (0.32) ALDH1A1
Carbon Monoxide SCHEMBL11677050 0.67 MEN1 (0.31) ALDH1A1
SCHEMBL7557905 0.67 ACHE (0.43) TAAR1ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US claimed
US-8436111-B2 Nickel catalyst system for the preparation of high CIS polybutadiene BRIDGESTONE CORPORATION (JP) 2013-05-07 US disclosed
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US disclosed