SCHEMBL4268682

SCHEMBL4268682

OCc1ccccc1-c1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.54
▸ STAT1 P42224 1/20 0.54
▸ PARP1 P09874 1/20 0.36
▸ ATR Q13535 1/20 0.35
▸ CHEK1 O14757 1/20 0.33
▸ WEE1 P30291 1/20 0.33
▸ TRPV1 Q8NER1 1/20 0.32
▸ TERT O14746 1/20 0.32
▸ CBFB Q13951 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2849607 0.84 STAT3 (0.58) STAT3STAT1
SCHEMBL4268982 0.83 STAT3 (0.55) STAT3STAT1
SCHEMBL11328879 0.82 STAT3 (0.56) STAT3STAT1
SCHEMBL6892151 0.81 STAT3 (0.58) STAT3STAT1
SCHEMBL7269032 0.81 STAT3 (0.58) STAT3STAT1
SCHEMBL27579991 0.81 STAT3 (0.58) STAT3STAT1
SCHEMBL10482856 0.81 STAT3 (0.58) STAT3STAT1
SCHEMBL9764318 0.81 STAT3 (0.58) STAT3STAT1
SCHEMBL1998702 0.80 STAT3 (0.56) STAT3STAT1
SCHEMBL311440 0.79 STAT3 (0.55) STAT3STAT1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521551-B2 Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy MIRAVANT PHARMACEUTICALS, INC. (US) 2009-04-21 — — US disclosed
US-7521551-B2 Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy MIRAVANT PHARMACEUTICALS, INC. (US) 2009-04-21 — — US disclosed
US-20080275232-A1 CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY MIRAVANT PHARMACEUTICALS, INC. 2008-11-06 — — US disclosed
US-20080275232-A1 CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY MIRAVANT PHARMACEUTICALS, INC. 2008-11-06 — — US disclosed
US-20050020560-A1 Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy MIRAVANT PHARMACEUTICALS, INC. 2005-01-27 — — US disclosed
US-20050020560-A1 Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy MIRAVANT PHARMACEUTICALS, INC. 2005-01-27 — — US disclosed
US-6794505-B1 Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy MIRAVANT PHARMACEUTICALS, INC. 2004-09-21 — — US disclosed
US-6794505-B1 Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy MIRAVANT PHARMACEUTICALS, INC. 2004-09-21 — — US disclosed
WO-2001074818-A1 CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY MIRAVANT PHARMACEUTICALS, INC. (US) 2001-10-11 — — WO disclosed
WO-2001074818-A1 CHLORINS WITH FUSED RINGS FOR USE IN PHOTODYNAMIC THERAPY MIRAVANT PHARMACEUTICALS, INC. (US) 2001-10-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275232-A1 CHLORINS POSSESSING FUSED RING SYSTEMS USEFUL AS PHOTOSELECTIVE COMPOUNDS FOR PHOTODYNAMIC THERAPY PPOX, HMBS, DDT STAT3 3696/4885STAT1 3561/4885PARP1 1691/4885
US-20050020560-A1 Chlorins processing fused ring systems useful as photoselective compounds for photodynamic therapy PPOX, HMBS, DDT STAT3 3916/4885STAT1 3672/4885PARP1 1524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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