Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487811 | 0.82 | KMT2A (0.43) | KDM4CKDM5BDAOTAAR1 | |
| SCHEMBL7493650 | 0.75 | AHR (0.57) | KDM4CKDM5BCHRM2CHRM1CHRM3 | |
| SCHEMBL8802300 | 0.73 | KMT2A (0.41) | DAOTAAR1RAPGEF4 | |
| SCHEMBL6600286 | 0.72 | LOXL2 (0.50) | KDM4CKDM5BDAO | |
| SCHEMBL23719038 | 0.72 | CNR2 (0.51) | IDH1CHRM2CHRM1CHRM3HTR1B | |
| SCHEMBL2099512 | 0.71 | CHRM2 (0.66) | CHRM2CHRM1CHRM3HTR1BTAAR1 | |
| SCHEMBL17204641 | 0.70 | GPR84 (0.52) | KDM4CKDM5BIDH1DAO | |
| SCHEMBL18355946 | 0.70 | MAOB (0.67) | IDH1CHRM2CHRM1CHRM3HTR1B | |
| SCHEMBL5648684 | 0.70 | CNR2 (0.52) | IDH1CHRM2CHRM1CHRM3CNR2 | |
| SCHEMBL13880096 | 0.69 | MAOB (0.62) | IDH1CHRM2CHRM1CHRM3HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047870-B | Preparation method of 7-alkyl indole derivative | 浙江工业大学 | 2021-10-12 | — | — | CN | disclosed |
| CN-112047870-A | Preparation method of 7-alkyl indole derivative | 浙江工业大学 | 2020-12-08 | — | — | CN | disclosed |