Dl-Tryptophan

Dl-Tryptophan

SCHEMBL28496362

NC(CO)C(=O)O.NC(Cc1c[nH]c2ccccc12)C(=O)O.NC(Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.68
KDM4E B2RXH2 3/20 0.68
MAPT P10636 3/20 0.68
MEN1 O00255 2/20 0.68
LMNA P02545 2/20 0.68
TSHR P16473 2/20 0.68
BLM P54132 2/20 0.68
PMP22 Q01453 2/20 0.68
MPO P05164 1/20 0.68
HIF1A Q16665 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.50
HSP90AA1 P07900 1/20 0.49
HSP90AB1 P08238 1/20 0.49
LTA4H P09960 1/20 0.49
PLA2G2A P14555 1/20 0.49
HTR1A P08908 2/20 0.49
HTR2A P28223 2/20 0.49
HTR2C P28335 2/20 0.49
SLC6A4 P31645 2/20 0.49
HTR7 P34969 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL14691207 0.96 KDM4E (0.63) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL29013076 0.96 KMT2A (0.63) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL7943446 0.96 KMT2A (0.74) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL78589 0.96 KMT2A (0.74) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL28059654 0.96 KMT2A (0.74) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL634683 0.96 KMT2A (0.74) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL28149832 0.96 KMT2A (0.74) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL11361648 0.95 KMT2A (0.73) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL22635843 0.92 KMT2A (0.58) KMT2AKDM4EMAPTMEN1LMNA
D-Tryptophan SCHEMBL14691185 0.92 KDM4E (0.57) KMT2AKDM4EMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111995659-B ACE inhibitory peptide derived from peony seed meal 福州大学 2021-10-29 CN disclosed
CN-111995659-A ACE inhibitory peptide derived from peony seed meal 福州大学 2020-11-27 CN disclosed