Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | MPO | P05164 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL28059654 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL634683 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL7943446 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL28149832 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL11361648 | 0.99 | KMT2A (0.73) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL28496362 | 0.96 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL8634348 | 0.96 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL8634349 | 0.96 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL4287653 | 0.95 | KMT2A (0.67) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL4551161 | 0.94 | KDM4E (0.65) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7713 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114373510-B | Metabolic marker for diagnosing or monitoring lung cancer and screening method and application thereof | 武汉迈特维尔医学科技有限公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2023083197-A1 | METABOLIC MARKER FOR DIAGNOSING OR MONITORING LUNG CANCER, AND SCREENING METHOD THEREFOR AND USE THEREOF | 武汉迈特维尔医学科技有限公司 | 2023-05-19 | — | — | WO | claimed |
| CN-115025204-A | Dipeptide compound for inhibiting A beta 42 aggregation and reducing cytotoxic effect thereof | 王大勇 | 2022-09-09 | — | — | CN | claimed |
| CN-114373510-A | Metabolic marker for lung cancer diagnosis or monitoring and screening method and application thereof | 武汉迈特维尔生物科技有限公司 | 2022-04-19 | — | — | CN | claimed |
| US-11260027-B2 | Donor organ pre-treatment formulation | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2022-03-01 | — | — | US | claimed |
| CN-112641956-A | Preparation and application of peptide-metal-drug self-assembly nanoparticles for resisting Alzheimer's disease | 福州大学 | 2021-04-13 | — | — | CN | claimed |
| US-20200281190-A1 | ORGAN PRECONDITIONING FORMULATION WITH MITOCHONDRIAL ELONGATING AGENTS | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2020-09-10 | — | — | US | claimed |
| CN-110178835-A | A kind of acoustic control myocardial preservation perfusion system | 胡行健 | 2019-08-30 | — | — | CN | claimed |
| US-20180338963-A1 | DONOR ORGAN PRE-TREATMENT FORMULATION | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2018-11-29 | — | — | US | claimed |
| WO-2017019214-A1 | DONOR ORGAN PRE-TREATMENT FORMULATION | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-02-02 | — | — | WO | claimed |
| WO-2012146774-A1 | OLIGOSACCHARIDE CONJUGATES IN THE PREVENTION OF ISCHEMIA-REPERFUSION INJURY | ENDOTIS PHARMA (FR) | 2012-11-01 | — | — | WO | claimed |
| US-6358501-B1 | USED AS INTERFACE-ACTIVE SUBSTANCES | GOLDSCHMIDT GMBH (DE) | 2002-03-19 | — | — | US | claimed |
| US-12037618-B2 | PH20 polypeptide variants, formulations and uses thereof | HALOZYME, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240229001-A1 | NOVEL METALLOPROTEASES | DANISCO US INC (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240228542-A1 | LYTIC DOMAIN FUSION CONSTRUCTS, CHECKPOINT INHIBITORS, AND METHODS OF MAKING AND USING SAME | A28 THERAPEUTICS INC (US) | 2024-07-11 | — | — | US | disclosed |
| EP-4396320-A2 | LAUNDRY COMPOSITIONS FOR CLEANING | Danisco US Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-1995009913-A9 | HUMAN MONOCYTE/MACROPHAGE DERIVED METALLOPROTEINASE INHIBITOR | — | 1995-06-15 | — | — | WO | disclosed |
| WO-1995009913-A1 | HUMAN MONOCYTE/MACROPHAGE DERIVED METALLOPROTEINASE INHIBITOR | INCYTE PHARMACEUTICALS, INC. (US) | 1995-04-13 | — | — | WO | disclosed |
| US-5051185-A | Cleaning and regeneration of body fluids by adsorption of microglobulins | ASAHI KASEI KOGYO K.K. (JP) | 1991-09-24 | — | — | US | disclosed |
| EP-0319144-A1 | Adsorbent of beta 2-microglobulin | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-06-07 | — | — | EP | disclosed |