Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | MPO | P05164 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL28059654 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL78589 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL634683 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL28149832 | 1.00 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL11361648 | 0.99 | KMT2A (0.73) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL28496362 | 0.96 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL8634348 | 0.96 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL8634349 | 0.96 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL4287653 | 0.95 | KMT2A (0.67) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL4551161 | 0.94 | KDM4E (0.65) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262017-B1 | CONTAINING A CELL ADHESION-RELATED AMINO ACID SEQUENCE, AND TO DEVICES AND BIOMATERIALS FOR IMPLANTATION COATED WITH OR INCORPORATING PEPTIDES CONTAINING THAT SEQUENCE. | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2001-07-17 | — | — | US | disclosed |
| EP-0877620-A4 | PEPTIDES FOR ALTERING OSTEOBLAST ADHESION | RENSSELAER POLYTECH INST (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0877620-A1 | PEPTIDES FOR ALTERING OSTEOBLAST ADHESION | RENSSELAER POLYTECHNIC INSTITUTE (US) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997025999-A1 | PEPTIDES FOR ALTERING OSTEOBLAST ADHESION | RENSSELAER POLYTECHNIC INSTITUTE (US) | 1997-07-24 | — | — | WO | disclosed |