Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29992673 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GPR119KMT2AMEN1MAPT | |
| SCHEMBL28497084 | 1.00 | L3MBTL1 (0.45) | L3MBTL1GPR119KMT2AMEN1MAPT | |
| SCHEMBL30718466 | 0.90 | GPR119 (0.44) | L3MBTL1GPR119KMT2AMEN1MAPT | |
| SCHEMBL17631665 | 0.88 | SMN1; SMN2 (0.44) | KMT2AMEN1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL19281700 | 0.88 | SMN1; SMN2 (0.44) | KMT2AMEN1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL29992723 | 0.85 | L3MBTL1 (0.46) | L3MBTL1GPR119KMT2AMEN1MAPT | |
| SCHEMBL28488536 | 0.85 | L3MBTL1 (0.46) | L3MBTL1GPR119KMT2AMEN1MAPT | |
| SCHEMBL28488534 | 0.85 | L3MBTL1 (0.46) | L3MBTL1GPR119KMT2AMEN1MAPT | |
| SCHEMBL30248188 | 0.84 | ADORA2A (0.45) | L3MBTL1GPR119KMT2AMEN1MAPT | |
| SCHEMBL30718471 | 0.83 | GPR119 (0.49) | L3MBTL1GPR119KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111592534-A | Novel compounds | 特殊治疗有限公司 | 2020-08-28 | — | — | CN | disclosed |