Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209075 | 0.84 | KDM4E (0.38) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL28507921 | 0.83 | CYSLTR2 (0.31) | — | |
| SCHEMBL28496145 | 0.81 | ALDH1A1 (0.31) | ALDH1A1HPGDNPSR1 | |
| SCHEMBL28498273 | 0.80 | ALOX5 (0.33) | SMN1; SMN2 | |
| SCHEMBL28507872 | 0.79 | ALOX5 (0.35) | — | |
| SCHEMBL28503104 | 0.79 | ALOX5 (0.35) | — | |
| SCHEMBL28509620 | 0.79 | ALOX5 (0.35) | — | |
| SCHEMBL28507871 | 0.78 | ALDH1A1 (0.33) | IGF1RALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL28499423 | 0.76 | — | — | |
| SCHEMBL16274821 | 0.73 | TRPV1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112040925-A | Use of specific benzylidene malonates for protecting skin against chemically induced stress | 默克专利股份有限公司 | 2020-12-04 | — | — | CN | disclosed |