SCHEMBL28499075

SCHEMBL28499075

C=C(CC)C(=O)ONC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MAPT P10636 3/20 0.54
POLB P06746 1/20 0.54
KMT2A Q03164 1/20 0.54
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 6/20 0.42
PRSS1 P07477 3/20 0.42
CTSG P08311 3/20 0.42
CTRB1 P17538 3/20 0.42
CMA1 P23946 3/20 0.42
GAA P10253 3/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
NAAA Q02083 1/20 0.41
MAPK1 P28482 1/20 0.40
AHR P35869 1/20 0.40
HDAC3 O15379 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4880508 0.81 ALDH1A1 (0.59) ALDH1A1MAPTPOLBKMT2ANPC1
SCHEMBL4315070 0.80 ALDH1A1 (0.61) ALDH1A1MAPTPOLBKMT2ANPC1
SCHEMBL10708110 0.76 LMNA (0.50) ALDH1A1MAPTPOLBKMT2ANPC1
SCHEMBL13479831 0.75 ALDH1A1 (0.66) ALDH1A1MAPTPOLBKMT2ANPC1
SCHEMBL28633509 0.74 EPHX2 (0.42) ALDH1A1MAPTPOLBKMT2ASMN1; SMN2
SCHEMBL6886046 0.73 ALDH1A1 (0.58) ALDH1A1MAPTPOLBKMT2ANPC1
SCHEMBL28052615 0.73 LMNA (0.59) ALDH1A1MAPTKMT2ASMN1; SMN2CES2
SCHEMBL2310273 0.73 ALDH1A1 (0.68) ALDH1A1MAPTPOLBKMT2ANPC1
SCHEMBL10424594 0.73 ALDH1A1 (0.73) ALDH1A1MAPTPOLBKMT2ANPC1
SCHEMBL13609052 0.72 KMT2A (0.56) ALDH1A1MAPTPOLBKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109467639-B Thermo-sensitive poly (acetamido ethyl acrylate-co-benzoyl amino ethyl acrylate) and preparation method thereof 河北大学 2020-11-24 CN claimed
CN-109467639-B Thermo-sensitive poly (acetamido ethyl acrylate-co-benzoyl amino ethyl acrylate) and preparation method thereof 河北大学 2020-11-24 CN disclosed
CN-109517107-A A kind of Thermo-sensitive poly- (propionamido ethyl propylene acid esters-co- benzamido ethyl propylene acid esters) and preparation method thereof 河北大学 2019-03-26 CN disclosed