Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28492096 | 0.81 | HTT (0.33) | CES2 | |
| SCHEMBL31224076 | 0.80 | AR (0.40) | POLQCYP2C19SMN1; SMN2NOTUM | |
| SCHEMBL28498687 | 0.79 | FSCN1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28501470 | 0.78 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL28490898 | 0.78 | FSCN1 (0.49) | GAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31223987 | 0.77 | AR (0.43) | CYP2C19NOTUM | |
| SCHEMBL28497420 | 0.75 | MAPT (0.41) | ALDH1A1KDM4EHPGDCYP2C19HSD17B10 | |
| SCHEMBL28250894 | 0.75 | SMN1; SMN2 (0.50) | POLQCES2SMN1; SMN2 | |
| SCHEMBL28499158 | 0.73 | GAA (0.36) | GAAALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL29131831 | 0.73 | CA1 (0.41) | GAAALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483364-B | Indolone sulfone compound and synthesis method thereof | 台州学院 | 2020-12-25 | — | — | CN | claimed |
| CN-110483364-B | Indolone sulfone compound and synthesis method thereof | 台州学院 | 2020-12-25 | — | — | CN | disclosed |