Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28356743 | 0.83 | ALDH1A1 (0.36) | ALDH1A1STAT3NCEH1LMNAFSCN1 | |
| SCHEMBL28498687 | 0.83 | FSCN1 (0.33) | ALDH1A1FSCN1RAB9A | |
| SCHEMBL28492096 | 0.81 | HTT (0.33) | FSCN1MAPT | |
| SCHEMBL28490898 | 0.81 | FSCN1 (0.49) | ALDH1A1FSCN1MAPTMEN1KMT2A | |
| SCHEMBL28497420 | 0.79 | MAPT (0.41) | ALDH1A1LMNARAB9AMAPTCYP1A2 | |
| SCHEMBL31223908 | 0.78 | XDH (0.33) | ALDH1A1NCEH1LMNACYP1A2MEN1 | |
| SCHEMBL28499201 | 0.78 | GAA (0.35) | ALDH1A1 | |
| SCHEMBL28147704 | 0.78 | POLB (0.32) | ALDH1A1STAT3NCEH1PDGFRACDK5 | |
| SCHEMBL28499158 | 0.77 | GAA (0.36) | ALDH1A1MAPT | |
| SCHEMBL29131831 | 0.77 | CA1 (0.41) | ALDH1A1LMNARAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483364-B | Indolone sulfone compound and synthesis method thereof | 台州学院 | 2020-12-25 | — | — | CN | claimed |
| CN-115650980-A | Oxindole compound and preparation method and application thereof | 江西师范大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-114105978-A | Oxindole compound and preparation method and application thereof | 江西师范大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-110483364-B | Indolone sulfone compound and synthesis method thereof | 台州学院 | 2020-12-25 | — | — | CN | disclosed |