Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28498687 | 0.87 | FSCN1 (0.33) | CYP2A6ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28250213 | 0.80 | KDM4E (0.37) | POLBCYP2A6ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28499158 | 0.78 | GAA (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL31042816 | 0.77 | FFAR1 (0.35) | POLBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29213679 | 0.74 | HCRTR1 (0.36) | POLBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28501470 | 0.73 | ALDH1A1 (0.34) | ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL28490898 | 0.73 | FSCN1 (0.49) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL28492096 | 0.73 | HTT (0.33) | — | |
| SCHEMBL24106352 | 0.72 | ALDH1A1 (0.50) | POLBALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28497420 | 0.71 | MAPT (0.41) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969875-A | Synthesis method of thioester functionalized 2-oxoindole | 南通大学 | 2023-10-31 | — | — | CN | claimed |
| CN-110483364-B | Indolone sulfone compound and synthesis method thereof | 台州学院 | 2020-12-25 | — | — | CN | claimed |
| CN-116969875-A | Synthesis method of thioester functionalized 2-oxoindole | 南通大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-115650980-A | Oxindole compound and preparation method and application thereof | 江西师范大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-114105978-A | Oxindole compound and preparation method and application thereof | 江西师范大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-110483364-B | Indolone sulfone compound and synthesis method thereof | 台州学院 | 2020-12-25 | — | — | CN | disclosed |