Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 9/20 | 0.51 |
| ▸ | CHUK | O15111 | 7/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.50 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495134 | 0.86 | SLC6A4 (0.52) | IKBKBFFAR4 | |
| SCHEMBL30640278 | 0.86 | SLC6A4 (0.52) | IKBKBFFAR4 | |
| SCHEMBL24578005 | 0.85 | BCAT2 (0.50) | CTNNB1SIRT2SIRT1BCAT2SCN9A | |
| SCHEMBL24579568 | 0.72 | SLC6A3 (0.61) | FFAR4 | |
| SCHEMBL24579567 | 0.72 | HDAC7 (0.56) | FFAR4 | |
| SCHEMBL30903648 | 0.72 | IKBKB (0.72) | IKBKBCHUKIKBKE | |
| SCHEMBL20549991 | 0.72 | IKBKB (0.72) | IKBKBCHUKIKBKE | |
| SCHEMBL920637 | 0.71 | PARP10 (0.56) | CTNNB1SIRT2SIRT1PARP10FFAR4 | |
| SCHEMBL30974625 | 0.71 | CTNNB1 (0.47) | CTNNB1SIRT2SIRT1BCAT2SCN9A | |
| SCHEMBL29250440 | 0.71 | CTNNB1 (0.47) | CTNNB1SIRT2SIRT1BCAT2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079830-B | Inhibitor containing fused ring derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-112079830-A | Fused ring-containing derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2020-12-15 | — | — | CN | disclosed |