SCHEMBL285008

SCHEMBL285008

CN(C)CCCNC(=O)OC(C)(C)C

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.66
MEN1 O00255 1/20 0.57
GAA P10253 1/20 0.57
KMT2A Q03164 1/20 0.57
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
CA12 O43570 6/20 0.50
CA1 P00915 6/20 0.50
CA2 P00918 6/20 0.50
CA9 Q16790 6/20 0.50
CA14 Q9ULX7 1/20 0.46
DNM1 Q05193 1/20 0.45
EPHX1 P07099 1/20 0.43
HTT P42858 1/20 0.42
STK17B O94768 1/20 0.42
STK17A Q9UEE5 1/20 0.42
KDM4E B2RXH2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15680567 0.95 TDP1 (0.64) TDP1MEN1GAAKMT2AMAOA
SCHEMBL4125770 0.93 TDP1 (0.58) TDP1MEN1GAAKMT2AMAOA
SCHEMBL34463500 0.93 TDP1 (0.67) TDP1MEN1GAAKMT2AMAOA
SCHEMBL4120360 0.90 TDP1 (0.54) TDP1MEN1GAAKMT2AMAOA
SCHEMBL14540437 0.89 CA14 (0.59) TDP1MEN1GAAKMT2AMAOA
SCHEMBL5217505 0.89 TDP1 (0.54) TDP1MEN1GAAKMT2AMAOA
SCHEMBL13377000 0.89 TDP1 (0.66) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1979026 0.89 TDP1 (0.55) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1931261 0.88 DNM1 (0.61) TDP1MEN1GAAKMT2AMAOA
SCHEMBL1930544 0.88 DNM1 (0.61) TDP1MEN1GAAKMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119913158-A Nucleic acid aptamer with zwitterionic modification and preparation method thereof 浙江工业大学 2025-05-02 CN disclosed
EP-3805214-B1 JAK3 SELECTIVE INHIBITOR UNIV PEKING SHENZHEN GRADUATE SCHOOL (CN) 2023-07-05 EP disclosed
WO-2023279211-A1 METAL-CONTAINING POLYMERS FOR MASS CYTOMETRY THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2023-01-12 WO disclosed
US-10227333-B2 Inhibition of OLIG2 activity Curtana Pharmaceuticals, Inc. (US) 2019-03-12 US disclosed
WO-2018081797-A1 PERIPHERAL MODIFICATIONS ON POCKET-REDESIGNED VANCOMYCIN ANALOGS SYNERGISTICALLY IMPROVE ANTIMICROBIAL POTENCY AND DURABILITY THE SCRIPPS RESEARCH INSTITUTE (US) 2018-05-03 WO disclosed
US-9580749-B2 Dyes and labeled molecules BIOTIUM, INC. (US) 2017-02-28 US disclosed
CN-103936716-B Tool muscarinic receptor antagonists and the diamide compound of beta 2 adrenoreceptor agonists activity 施万呼吸有限责任公司 2016-09-07 CN disclosed
US-20160237069-A1 INHIBITION OF OLIG2 ACTIVITY Curtana Pharmaceuticals, Inc. 2016-08-18 US disclosed
US-20160237069-A1 INHIBITION OF OLIG2 ACTIVITY Curtana Pharmaceuticals, Inc. 2016-08-18 US disclosed
US-9102835-B2 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. (US) 2015-08-11 US disclosed
US-7659070-B2 Charge switch nucleotides PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2010-02-09 US disclosed
US-20100009454-A1 METHODS OF USING DYES IN ASSOCIATION WITH NUCLEIC ACID STAINING OR DETECTION AND ASSOCIATED TECHNOLOGY BIOTIUM, INC. 2010-01-14 US disclosed
US-7625701-B2 Triphosphate having gamma-phosphate with detectable group attached; detection using charge coupled device camera or photodiode; labeled nucleotide phosphate (e.g., gamma -NP-Dye) that on cleavage of phosphate detectable moiety (e.g., PPi-Dye) has different charge compared to intact nucleotide phosphate PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2009-12-01 US disclosed
US-7601498-B2 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. (US) 2009-10-13 US disclosed
US-20080206764-A1 Flowcell system for single molecule detection PACIFIC BIOSCIENCES (US) 2008-08-28 US disclosed
EP-1947105-A1 Method for single-step attachment of a label to target molecules Mirus Bio Corporation (US) 2008-07-23 EP disclosed
US-20080153095-A1 CHARGE SWITCH NUCLEOTIDES PACIFIC BIOSCIENCES (US) 2008-06-26 US disclosed
US-7326780-B2 Label (fluorescence-emitting molecule, hapten-containing molecule, protein, or radioactive chemical) attached to N-(2-chloroethyl)-N-methylaminobenzylamino ligand by a spacer forming a neutralized quaternary ammonium group for covalent attachment to DNA, RNA, or siRNA MIRUS BIO CORPORATION (US) 2008-02-05 US disclosed
US-20060211028-A1 Dimeric and trimeric nucleic acid dyes, and associated systems and methods ALLELOGIC BIOSCIENCES CORPORATION 2006-09-21 US disclosed
US-20060211029-A1 Methods of using dyes in association with nucleic acid staining or detection and associated technology BIOTIUM, INC. 2006-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211028-A1 Dimeric and trimeric nucleic acid dyes, and associated systems and methods DNA2, POLRMT, POLL TDP1 105/4885MEN1 3398/4885GAA 544/4885
US-10227333-B2 Inhibition of OLIG2 activity GLI2, ING2, GMFG TDP1 3233/4885MEN1 2974/4885GAA 2405/4885
US-20060211029-A1 Methods of using dyes in association with nucleic acid staining or detection and associated technology HNRNPLL, HNRNPL, HNRNPH3 TDP1 287/4885MEN1 3185/4885GAA 1454/4885
US-20160237069-A1 INHIBITION OF OLIG2 ACTIVITY GLI2, ING2, GMFG TDP1 3233/4885MEN1 2974/4885GAA 2405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.